Current tools for the identification of miRNA genes and their targets
The discovery of microRNAs (miRNAs), almost 10 years ago, changed dramatically our
perspective on eukaryotic gene expression regulation. However, the broad and important …
perspective on eukaryotic gene expression regulation. However, the broad and important …
A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p …
H Xue, G Yuan, X Guo, Q Liu, J Zhang, X Gao, X Guo… - Autophagy, 2016 - Taylor & Francis
Hypoxia induces protective autophagy in glioblastoma cells and new therapeutic avenues
that target this process may improve the outcome for glioblastoma patients. Recent studies …
that target this process may improve the outcome for glioblastoma patients. Recent studies …
Small RNAs analysis in CLL reveals a deregulation of miRNA expression and novel miRNA candidates of putative relevance in CLL pathogenesis
S Marton, MR Garcia, C Robello, H Persson… - Leukemia, 2008 - nature.com
MicroRNAs (miRNAs) are a novel class of small noncoding RNA molecules that regulate
gene expression by inducing degradation or translational inhibition of target mRNAs. There …
gene expression by inducing degradation or translational inhibition of target mRNAs. There …
De novo prediction of structured RNAs from genomic sequences
Growing recognition of the numerous, diverse and important roles played by non-coding
RNA in all organisms motivates better elucidation of these cellular components …
RNA in all organisms motivates better elucidation of these cellular components …
Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes
MicroRNAs (miRNAs) are short regulatory RNAs that inhibit target genes by complementary
binding in 3′ untranslated regions (3′ UTRs). They are one of the most abundant classes …
binding in 3′ untranslated regions (3′ UTRs). They are one of the most abundant classes …
GraphClust: alignment-free structural clustering of local RNA secondary structures
Motivation: Clustering according to sequence–structure similarity has now become a
generally accepted scheme for ncRNA annotation. Its application to complete genomic …
generally accepted scheme for ncRNA annotation. Its application to complete genomic …
Heterogeneous ensemble approach with discriminative features and modified-SMOTEbagging for pre-miRNA classification
An ensemble classifier approach for microRNA precursor (pre-miRNA) classification was
proposed based upon combining a set of heterogeneous algorithms including support …
proposed based upon combining a set of heterogeneous algorithms including support …
RNA Editing in Trypanosoma brucei Requires Three Different Editosomes
J Carnes, JR Trotter, A Peltan, M Fleck… - Molecular and cellular …, 2008 - Taylor & Francis
Trypanosoma brucei has three distinct∼ 20S editosomes that catalyze RNA editing by the
insertion and deletion of uridylates. Editosomes with the KREN1 or KREN2 RNase III type …
insertion and deletion of uridylates. Editosomes with the KREN1 or KREN2 RNase III type …
The liverwort Pellia endiviifolia shares microtranscriptomic traits that are common to green algae and land plants
S Alaba, P Piszczalka, H Pietrykowska… - New …, 2015 - Wiley Online Library
Liverworts are the most basal group of extant land plants. Nonetheless, the molecular
biology of liverworts is poorly understood. Gene expression has been studied in only one …
biology of liverworts is poorly understood. Gene expression has been studied in only one …
Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans
Mirtrons are intronic hairpin substrates of the dicing machinery that generate functional
microRNAs. In this study, we describe experimental assays that defined the essential …
microRNAs. In this study, we describe experimental assays that defined the essential …