The protozoan Trypanosoma cruzi, its mammalian reservoirs, and vectors have existed in
nature for millions of years. The human infection, named Chagas disease, is a major public …

As Chagas disease remains prevalent in the Americas, it is important that healthcare
professionals and researchers are aware of the screening, diagnosis, monitoring, and …

Background A century after its discovery, Chagas disease still represents a major neglected
tropical threat. Accurate diagnostics tools as well as surrogate markers of parasitological …

An international study was performed by 26 experienced PCR laboratories from 14 countries
to assess the performance of duplex quantitative real-time PCR (qPCR) strategies on the …

Over the last 30 years, concomitant with successful transnational disease control programs
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …

Background This report describes a real-time PCR (Q-PCR) strategy to quantify
Trypanosoma cruzi (T. cruzi) DNA in peripheral blood samples from Chagas disease …

Congenital infection with Trypanosoma cruzi is a global problem, occurring on average in
5% of children born from chronically infected mothers in endemic areas, with variations …

In this study, we report and discuss the results generated from over 20 years of studies of the
Trypanosoma cruzi sylvatic transmission cycle. Our results have uncovered new aspects …

Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating
illness of major significance throughout Latin America and an emergent threat to global …

Background. One hundred years after the discovery of Chagas disease, it remains a major
neglected tropical disease. Chronic Chagas heart disease (cChHD) is the most severe …