Oral and esophageal squamous cell carcinomas harbor a diverse microbiome that differs
compositionally from precancerous and healthy tissues. Though causality is yet to be …

The six members of the family of insulin-like growth factor (IGF) binding proteins (IGFBPs)
were originally characterized as passive reservoirs of circulating IGFs, but they are now …

Determination of the role of insulin-like growth factor (IGF) family components in
carcinogenesis of several human tumors is based on numerous epidemiological and pre …

Abstract Olfactomedin 4 (OLFM4) is an olfactomedin domain-containing glycoprotein.
Multiple signaling pathways and factors, including NF-κB, Wnt, Notch, PU. 1, retinoic acids …

This study investigates for the first time the crosstalk between stromal fibroblasts and cancer
stem cell (CSC) biology in head and neck squamous cell carcinomas (HNSCC), with the …

With the increasing incidence of oral cancer in the world, it has become a hotspot to explore
the pathogenesis and prevention of oral cancer. It has been proved there is a strong link …

Insulin‐like growth factor binding protein‐3 (IGFBP‐3) is a key regulatory molecule of the
IGF axis and can function in a tissue‐specific way as both a tumor suppressor and promoter …

OBJECTIVE Despite intensive medical treatment, patients with glioblastoma (grade IV
glioma [GBM]) have a low 5-year survival rate of 5.5%. In this study, the authors tried to …

Multiple genomic and proteomic studies have suggested that peripheral blood mononuclear
cells (PBMCs) respond to tumor secretomes and thus could provide possible avenues for …

Loco-regional recurrence in 50% of oral squamous cell carcinoma (OSCC) patients poses
major challenge for oncologists. Lack of biomarkers that can predict disease aggressiveness …