The extracellular matrix is a fundamental, core component of all tissues and organs, and is
essential for the existence of multicellular organisms. From the earliest stages of organism …

Ferroptosis is a new kind of regulated cell death that is characterized by highly iron-
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …

As a phenolic acid compound, caffeic acid (CA) can be isolated from different sources such
as tea, wine and coffee. Caffeic acid phenethyl ester (CAPE) is naturally occurring derivative …

The need for improved prediction of clinical response is driving the development of cancer
models with enhanced physiological relevance. A new concept of 'precision biomaterials' is …

Despite the remarkable advances in cancer diagnosis, treatment, and management over the
past decade, malignant tumors remain a major public health problem. Further progress in …

Signal transducer and activator of transcription 3 (STAT3) is one of the crucial transcription
factors, responsible for regulating cellular proliferation, cellular differentiation, migration …

The introduction of CDK4/6 inhibitors in combination with endocrine therapy (ET) represents
the most relevant advance in the management of hormone receptor (HR) positive, HER2 …

Air pollution plays an important role in the mortality and morbidity of chronic airway
diseases, such as asthma and chronic obstructive pulmonary disease (COPD). Particulate …

Primary tumors secrete a variety of factors to turn distant microenvironments into favorable
and fertile 'soil'for subsequent metastases. Among these 'seeding'factors that initiate pre …

Transglutaminase type 2 (TG2) is the most ubiquitously expressed and well characterized
member of the transglutaminase family. It is a ubiquitous multifunctional enzyme implicated …