Mendelian randomization
Mendelian randomization (MR) is a term that applies to the use of genetic variation to
address causal questions about how modifiable exposures influence different outcomes …
address causal questions about how modifiable exposures influence different outcomes …
Mendelian randomization: concepts and scope
RC Richmond, GD Smith - Cold Spring …, 2022 - perspectivesinmedicine.cshlp.org
Mendelian randomization (MR) is a method of studying the causal effects of modifiable
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …
Guidelines for performing Mendelian randomization investigations: update for summer 2023
This paper provides guidelines for performing Mendelian randomization investigations. It is
aimed at practitioners seeking to undertake analyses and write up their findings, and at …
aimed at practitioners seeking to undertake analyses and write up their findings, and at …
The associations between modifiable risk factors and nonalcoholic fatty liver disease: A comprehensive Mendelian randomization study
J **e, H Huang, Z Liu, Y Li, C Yu, L Xu, C Xu - Hepatology, 2023 - journals.lww.com
Conclusions: Genetically predicted alcohol frequency, elevated serum liver enzymes, poor
physical condition, obesity traits, T2DM, and hypertension were associated with an …
physical condition, obesity traits, T2DM, and hypertension were associated with an …
[HTML][HTML] Statistical methods for Mendelian randomization in genome-wide association studies: a review
Genome-wide association studies have yielded thousands of associations for many
common diseases and disease-related complex traits. The identified associations made it …
common diseases and disease-related complex traits. The identified associations made it …
[КНИГА][B] Mendelian randomization: methods for causal inference using genetic variants
S Burgess, SG Thompson - 2021 - books.google.com
Mendelian Randomization: Methods For Causal Inference Using Genetic Variants provides
thorough coverage of the methods and practical elements of Mendelian randomization …
thorough coverage of the methods and practical elements of Mendelian randomization …
Sociology, genetics, and the coming of age of sociogenomics
Recent years have seen the birth of sociogenomics via the infusion of molecular genetic
data. We chronicle the history of genetics, focusing particularly on post-2005 genome-wide …
data. We chronicle the history of genetics, focusing particularly on post-2005 genome-wide …
Association of gut microbiome and primary liver cancer: A two‐sample Mendelian randomization and case–control study
J Ma, J Li, C **, J Yang, C Zheng, K Chen… - Liver …, 2023 - Wiley Online Library
Abstract Background and Aims Observational epidemiology studies suggested a
relationship between the gut microbiome and primary liver cancer. However, the causal …
relationship between the gut microbiome and primary liver cancer. However, the causal …
Understanding the assumptions underlying Mendelian randomization
With the rapidly increasing availability of large genetic data sets in recent years, Mendelian
Randomization (MR) has quickly gained popularity as a novel secondary analysis method …
Randomization (MR) has quickly gained popularity as a novel secondary analysis method …