Cooperation between microbes can enable microbial communities to survive in harsh
environments. Enzymatic deactivation of antibiotics, a common mechanism of antibiotic …

Neutrophils are the most abundant leukocyte in humans and provide a critical early line of
defense as part of our innate immune system. We perform a comprehensive, genome-wide …

Flow cytometry is widely used to measure gene expression and other molecular biological
processes with single cell resolution via fluorescent probes. Flow cytometers output data in …

An important challenge for primary or secondary analysis of cytometry data is how to
facilitate productive collaboration between domain and quantitative experts. Domain experts …

The social amoeba Dictyostelium discoideum is a model for a wide range of biological
processes including chemotaxis, cell-cell communication, phagocytosis, and development …

Mammalian membrane proteins perform essential physiologic functions that rely on their
accurate insertion and folding at the endoplasmic reticulum (ER). Using forward and arrayed …

The plant corepressor TPL is recruited to diverse chromatin contexts, yet its mechanism of
repression remains unclear. Previously, we leveraged the fact that TPL retains its function in …

Changing environmental cues lead to the adjustment of cellular physiology by
phosphorylation signaling networks that typically center around kinases as active effectors …

Microbial communities play a critical role in ecological processes, and their diversity is key to
their functioning. However, little is known about whether communities can regenerate …

Effective microbial bioprocessing relies on maintaining ideal cultivation conditions,
highlighting the necessity for tools that monitor and regulate cellular performance and …