There is a growing recognition that gliomas are complex tumors composed of neoplastic and
non-neoplastic cells, which each individually contribute to cancer formation, progression …

Gliomas are the most malignant and aggressive form of brain tumors, and account for the
majority of brain cancer related deaths. Malignant gliomas, including glioblastoma are …

Glioblastomas are lethal cancers characterized by florid angiogenesis promoted in part by
glioma stem cells (GSCs). Because hypoxia regulates angiogenesis, we examined hypoxic …

Radiobiological research over the past decades has provided evidence that cancer stem
cell content and the intrinsic radiosensitivity of cancer stem cells varies between tumours …

Unresectable glioblastoma (GBM) cells in the invading tumor edge can act as seeds for
recurrence. The molecular and phenotypic properties of these cells remain elusive. Here, we …

Purpose: The existence of cancer stem cells (CSCs) in breast cancer has profound
implications for cancer prevention. In this study, we evaluated sulforaphane, a natural …

Glioblastoma multiforme (GBM) is a primary malignant brain tumor characterized by a high
grade of malignancy and an extremely unfavorable prognosis. The current efficacy of …

Recent evidence suggests that many malignancies, including breast cancer, are driven by a
cellular subcomponent that displays stem cell-like properties. The protein phosphatase and …

Highly tumorigenic subpopulations of several solid cancers share characteristics with
somatic stem cells. We showed recently that cancer stem cells, or tumor-initiating cells …

Globally, breast cancer is the most frequently diagnosed cancer among women. The major
unresolved problems with metastatic breast cancer is recurrence after receiving objective …