Restoring susceptibility to aminoglycosides: Identifying small molecule inhibitors of enzymatic inactivation

AJ Magaña, J Sklenicka, C Pinilla… - RSC Medicinal …, 2023 - pubs.rsc.org
Growing resistance to antimicrobial medicines is a critical health problem that must be
urgently addressed. Adding to the increasing number of patients that succumb to infections …

Challenges & solutions for recent advancements in multi-drugs resistance tuberculosis: a review

P Yadav - Microbiology Insights, 2023 - journals.sagepub.com
In MDR-TB, mycobacterium is resistant to battlefront drugs like rifampicin and isoniazid. Now
it's an urgent global challenge for treatment & diagnosis because more than 50% of drugs …

Efflux pump effects on levofloxacin resistance in Mycobacterium abscessus

T Teng, S Chen, F Huo, J Jia, L Zhao… - Antimicrobial Agents …, 2024 - journals.asm.org
Mycobacterium abscessus (M. abscessus) inherently displays resistance to most antibiotics,
with the underlying drug resistance mechanisms remaining largely unexplored. Efflux pump …

Antisense agents against antibiotic-resistant bacteria

J Nezhadi, S Taghizadeh, E Khodadadi… - Current …, 2022 - benthamdirect.com
The dramatically increasing levels of antibiotic resistance are being seen worldwide and are
a significant threat to public health. Antibiotic and drug resistance is seen in various bacterial …