Molecular mechanisms for the anti-cancer effects of diallyl disulfide

L Yi, Q Su - Food and chemical toxicology, 2013 - Elsevier
Considerable evidence in recent years suggests that garlic has anti-proliferative effects
against various types of cancer. Garlic contains water-soluble and oil-soluble sulfur …

A review of potential anti-cancer properties of some selected medicinal plants grown in Iran

A Hamedi, M Bayat, Y Asemani… - Journal of Herbal Medicine, 2022 - Elsevier
Introduction The increasing number of cancer patients, together with the side effects of
current chemical treatments have encouraged the exploration of the potential of Iranian …

Anti-inflammatory, pro-apoptotic, and anti-proliferative effects of a methanolic neem (Azadirachta indica) leaf extract are mediated via modulation of the nuclear factor …

M Schumacher, C Cerella, S Reuter, M Dicato… - Genes & nutrition, 2011 - Springer
Azadirachta indica (neem tree) is used in traditional Indian medicine for its pharmacological
properties including cancer prevention and treatment. Here, we studied a neem extract's anti …

Anticancer bioactivity of compounds from medicinal plants used in European medieval traditions

MH Teiten, F Gaascht, M Dicato, M Diederich - Biochemical pharmacology, 2013 - Elsevier
Since centuries, natural compounds from plants, animals and microorganisms were used in
medicinal traditions to treat various diseases without a solid scientific basis. Recent studies …

Cell type-dependent ROS and mitophagy response leads to apoptosis or necroptosis in neuroblastoma

F Radogna, C Cerella, A Gaigneaux, C Christov… - Oncogene, 2016 - nature.com
A limiting factor in the therapeutic outcome of children with high-risk neuroblastoma is the
intrinsic and acquired resistance to common chemotherapeutic treatments. Here we …

Tilapia (Oreochromis mossambicus) antimicrobial peptide, hepcidin 1–5, shows antitumor activity in cancer cells

WT Chang, CY Pan, V Rajanbabu, CW Cheng… - Peptides, 2011 - Elsevier
The inhibitory function of tilapia hepcidin (TH) 1–5, an antimicrobial peptide, was not
examined in previous studies. In this study, we synthesized the TH1–5 peptide and tested …

SG1002 and catenated divalent organic sulfur compounds as promising hydrogen sulfide prodrugs

G Gojon, GA Morales - Antioxidants & Redox Signaling, 2020 - liebertpub.com
Significance: Sulfur has a critical role in protein structure/function and redox status/signaling
in all living organisms. Although hydrogen sulfide (H2S) and sulfane sulfur (SS) are now …

Chemical properties and mechanisms determining the anti-cancer action of garlic-derived organic sulfur compounds

C Cerella, M Dicato, C Jacob… - Anti-Cancer Agents in …, 2011 - ingentaconnect.com
Organic sulfur compounds (OSCs) derived from plants, fungi or bacteria can serve as
chemopreventive and/or chemotherapeutic agents and have been attracting medical and …

Coumarin polysulfides inhibit cell growth and induce apoptosis in HCT116 colon cancer cells

NEB Saidu, S Valente, E Bana, G Kirsch… - Bioorganic & medicinal …, 2012 - Elsevier
Coumarins and coumarin derivatives as well as diallyl polysulfides are well known as
anticancer drugs. In order to find new drugs with anticancer activities, we combined …

Garlic-derived natural polysulfanes as hydrogen sulfide donors: Friend or foe?

E Yagdi, C Cerella, M Dicato, M Diederich - Food and Chemical Toxicology, 2016 - Elsevier
In vitro and in vivo studies reported the anti-cancer potential of organosulfur compounds
(OSCs) as they trigger biological effects leading to cell cycle arrest with accumulation of cells …