Inflammation of the human lung is mediated in response to different stimuli (eg, physical,
radioactive, infective, pro-allergenic or toxic) such as cigarette smoke and environmental …

The lungs are exposed to reactive oxygen species oxygen (ROS) produced as a result of
inhalation of oxygen, as well as smoke and other air pollutants. Cell metabolism and the …

Collection of exhaled breath condensate (EBC) is a noninvasive method for obtaining
samples from the lungs. EBC contains large number of mediators including adenosine …

The lungs are directly exposed to higher oxygen concentrations than most other tissues.
Increased oxidative stress is a significant part of the pathogenesis of obstructive lung …

There has recently been an explosion of interest in the analysis of breath constituents as a
way of monitoring inflammation and oxidative stress in the lungs. Here we review the use of …

Asthma is a complex chronic inflammatory disease of the airways that involves the activation
of many inflammatory and structural cells, all of which release inflammatory mediators that …

There is ample evidence that allergic disorders, such as asthma, rhinitis, and atopic
dermatitis, are mediated by oxidative stress. Excessive exposure to reactive oxygen and …

Oxidative stress, specifically lipid peroxidation, is believed to contribute to the
pathophysiology of asthma. This review highlights the pathways through which reactive …

Endogenous airway acidification, as assessed by pH in expired breath condensate, has
been implicated in asthma pathophysiology. We measured pH in breath condensate of …

Symptoms of atopic asthma often disappear at puberty. However, asthmatic subjects in
clinical remission will frequently have a relapse later in life. The aim of this study was to …