Multipotent mesenchymal stromal cells (MSCs) represent a promising cell-based therapy in
regenerative medicine and for the treatment of inflammatory/autoimmune diseases …

A significant number of clinical trials have been undertaken to explore the use of
mesenchymal stem cells (MSCs) for the treatment of several diseases such as Crohn's …

Caused by the DNA monkeypox virus belonging to the orthopoxvirus genus and transmitted
between animals and humans and from human to human, monkeypox disease results in …

Articular cartilage injuries caused by traumatic, mechanical and/or by progressive
degeneration result in pain, swelling, subsequent loss of joint function and finally …

Cartilage-derived matrix (CDM) has emerged as a promising scaffold material for tissue
engineering of cartilage and bone due to its native chondroinductive capacity and its ability …

A previous study identified kartogenin (KGN) as a potent modulator of bone marrow
mesenchymal stem/stromal cell (BMSC) chondrogenesis. This initial report did not contrast …

Controlling the release of recombinant adeno-associated virus (rAAV) vectors from
biocompatible materials is a novel, attractive approach to increase the residence time and …

Recombinant adeno-associated viral (rAAV) vectors are clinically adapted gene transfer
vectors for direct human cartilage regenerative medicine. Their appropriate use in patients is …

Recombinant adeno-associated virus (rAAV) vectors are clinically adapted vectors to
durably treat human osteoarthritis (OA). Controlled delivery of rAAV vectors via polymeric …

Background: Application of the chondrogenic transforming growth factor beta (TGF-β) is an
attractive approach to enhance the intrinsic biological activities in damaged articular …