Exploring the anti‐inflammatory activity of sulforaphane

K Treasure, J Harris… - Immunology and Cell …, 2023 - Wiley Online Library
Dysregulation of innate immune responses can result in chronic inflammatory conditions.
Glucocorticoids, the current frontline therapy, are effective immunosuppressive drugs but …

Applications of the Keap1–Nrf2 system for gene and cell therapy

KM Kanninen, Y Pomeshchik, H Leinonen… - Free Radical Biology …, 2015 - Elsevier
Oxidative stress has been implicated to play a role in a number of acute and chronic
diseases including acute injuries of the central nervous system, neurodegenerative and …

NZ suppresses TLR4/NF-κB signalings and NLRP3 inflammasome activation in LPS-induced RAW264. 7 macrophages

P **ang, T Chen, Y Mou, H Wu, P **e, G Lu… - Inflammation …, 2015 - Springer
Objective The purpose of the present study was to evaluate the potential therapeutic effects
of NZ on lipopolysaccharide (LPS)-induced RAW264. 7 cells and explore its underlying …

Sulforaphane exerts anti-inflammatory effects against lipopolysaccharide-induced acute lung injury in mice through the Nrf2/ARE pathway

T Qi, FEI Xu, X Yan, S Li, H Li - … Journal of Molecular …, 2016 - spandidos-publications.com
Abstract Sulforaphane (1-isothiocyanate-4-methyl sulfonyl butane) is a plant extract
(obtained from cruciferous vegetables, such as broccoli and cabbage) and is known to exert …

Sulforaphane attenuates neutrophil ROS production, MPO degranulation and phagocytosis, but does not affect NET formation ex vivo and in vitro

S Wakasugi-Onogi, S Ma, RT Ruhee, Y Tong… - International journal of …, 2023 - mdpi.com
Sulforaphane has several effects on the human body, including anti-inflammation,
antioxidation, antimicrobial and anti-obesity effects. In this study, we examined the effect of …

Sulforaphane reduces the chronic inflammatory immune response of human dendritic cells

L Fernandez-Prades, M Brasal-Prieto, G Alba, V Martin… - Nutrients, 2023 - mdpi.com
Background: Sulforaphane (SFN) is an isothiocyanate of vegetable origin with potent
antioxidant and immunomodulatory properties. The characterization of its pleiotropic activity …

Prevention of Cyclophosphamide‐Induced Immunosuppression in Mice with the Antimicrobial Peptide Sublancin

S Wang, S Huang, Q Ye, X Zeng, H Yu… - Journal of …, 2018 - Wiley Online Library
Sublancin is a glycosylated antimicrobial peptide produced by Bacillus subtilis 168 with
combined antibacterial and immunomodulatory activities. The purpose of this study was to …

Broccoli and human health: Immunomodulatory effect of sulforaphane in a model of colon cancer

H Bessler, M Djaldetti - International journal of food sciences and …, 2018 - Taylor & Francis
The favourable properties of broccoli on human health are due to their abundant content of
vitamins, minerals and isothiocyanates, the sulforaphane (SFN) being the most important …

Sulforaphane attenuates activation of NLRP3 and NLRC4 inflammasomes but not AIM2 inflammasome

J Lee, H Ahn, EJ Hong, BS An, EB Jeung, GS Lee - Cellular immunology, 2016 - Elsevier
Sulforaphane (SFN), a compound within the isothiocyanate group of organosulfur
compounds originating from cruciferous vegetables, has gained attention for its antioxidant …

Quercitrin from Toona sinensis (Juss.) M.Roem. Attenuates Acetaminophen-Induced Acute Liver Toxicity in HepG2 Cells and Mice through Induction of Antioxidant …

VL Truong, SY Ko, M Jun, WS Jeong - Nutrients, 2016 - mdpi.com
Quercitrin is found in many kinds of vegetables and fruits, and possesses various bioactive
properties. The aim of the present study was to elucidate hepatoprotective mechanisms of …