In the 1970s, an unknown virus was suspected for documented cases of transfusion-
associated hepatitis, a phenomenon called non-A, non-B hepatitis. In 1989, the infectious …

Primary liver cancer is the sixth most commonly occurring cancer in the world and the
second largest contributor to cancer mortality. 1 Globally, the most common histology …

Abstract Background Hepatitis C virus (HCV) exhibits great genetic diversity and is classified
into 7 genotypes (GTs), with varied geographic prevalence. Until the recent development of …

The discovery of hepatitis C virus (HCV) in 1989 permitted basic research to unravel critical
components of a complex life cycle for this important human pathogen. HCV is a highly …

Background Because many persons with chronic hepatitis C virus (HCV) infection are
asymptomatic, population-based serologic studies are needed to estimate the prevalence of …

Hepatitis C virus (HCV) remains a significant global health challenge. Approximately 50
million people were living with chronic hepatitis C based on the World Health Organization …

International standardization and coordination of the nomenclature of variants of hepatitis C
virus (HCV) is increasingly needed as more is discovered about the scale of HCV‐related …

On the global scale, primary liver cancer is a major contributor to both cancer incidence and
mortality. It is the sixth most commonly occurring cancer in the world and the third largest …

In the 15 years since the discovery of hepatitis C virus (HCV), much has been learned about
its role as a major causative agent of human liver disease and its ability to persist in the face …

On the basis of phylogenetic analysis of nucleotide sequences, multiple genotypes and
subtypes of hepatitis C virus (HCV) have been identified. Characterization of these genetic …