XUV photoelectron spectroscopy (XPS) is a powerful method for investigating the electronic
structures of molecules. However, the correct interpretation of results in the condensed …

iLOV is an engineered flavin-binding fluorescent protein (FbFP) with applications for in vivo
cellular imaging. To expand the range of applications of FbFPs for multicolor imaging and …

We unveil the intimate relationship between protein dynamics and allostery by following the
trajectories of model proteins in their conformational and sequence spaces. Starting from a …

This study utilizes the FMN-dependent NADH: quinone oxidoreductase from Pseudomonas
aeruginosa PAO1 to investigate the effect of introducing an active site negative charge on …

Allosteric regulation is a powerful mechanism for controlling the efficiency of enzymes.
Deciphering the evolutionary mechanisms by which allosteric properties have been …

Enzymes are potent catalysts that increase biochemical reaction rates by several orders of
magnitude. Flavoproteins are a class of enzymes whose classification relies on their ability …

Modern quantum‐based methods are employed to model interaction of the flavin‐
dependent enzyme RutA with the uracil and oxygen molecules. This complex presents the …

Oxygenase activity of the flavin-dependent enzyme RutA is commonly associated with the
formation of flavin-oxygen adducts in the enzyme active site. We report the results of …

Abstract d-Arginine dehydrogenase from Pseudomonas aeruginosa (Pa DADH) catalyzes
the flavin-dependent oxidation of d-arginine and other d-amino acids. Here, we report the …

Ionizable residues and monoatomic ions in solution modulate enzyme catalysis and the
structural stability of proteins; however, the delicate interplay between these short-range …