The potential of the diverse chemistries present in natural products (NP) for biotechnology
and medicine remains untapped because NP databases are not searchable with raw data …

One-quarter of photosynthesis-derived carbon on Earth rapidly cycles through a set of short-
lived seawater metabolites that are generated from the activities of marine phytoplankton …

The 2015 Nobel Prize in Physiology or Medicine has been awarded to William C. Campbell,
Satoshi Omura, and Youyou Tu for the discovery of avermectins and artemisinin …

Actinomycetes are a diverse family of filamentous bacteria that produce a plethora of natural
products relevant for agriculture, biotechnology and medicine, including the majority of the …

Despite the over 100-y history of mass spectrometry, it remains challenging to link the large
volume of known chemical structures to the data obtained with mass spectrometers …

Metabolite profiling is critical in many aspects of the life sciences, particularly natural product
research. Obtaining precise information on the chemical composition of complex natural …

Starting with the earliest Streptomyces genome sequences, the promise of natural product
genome mining has been captivating: genomics and bioinformatics would transform …

Phytopathogenic fungi, causing significant economic and production losses, are becoming a
serious threat to global food security. Due to an increase in fungal resistance and the …

Species of the genus Trichoderma inhabit diverse environments and undergo a variety of
interactions with different other organisms. Mycoparasitic Trichoderma species are …

Many Fungi have a well-developed secondary metabolism. The diversity of fungal species
and the diversification of biosynthetic gene clusters underscores a nearly limitless potential …