Revitalizing ancient mitochondria with nano‐strategies: mitochondria‐remedying nanodrugs concentrate on disease control

X Long, M Liu, Y Nan, Q Chen, Z **ao… - Advanced …, 2024 - Wiley Online Library
Mitochondria, widely known as the energy factories of eukaryotic cells, have a myriad of vital
functions across diverse cellular processes. Dysfunctions within mitochondria serve as …

[HTML][HTML] Drug delivery to the brain: recent advances and unmet challenges

S Bhunia, N Kolishetti, A Vashist, A Yndart Arias… - Pharmaceutics, 2023 - mdpi.com
Brain cancers and neurodegenerative diseases are on the rise, treatments for central
nervous system (CNS) diseases remain limited. Despite the significant advancement in drug …

[HTML][HTML] Nanoplastics induces oxidative stress and triggers lysosome-associated immune-defensive cell death in the earthworm Eisenia fetida

Y Zhou, G He, H Jiang, K Pan, W Liu - Environment International, 2023 - Elsevier
Nanoplastics (NPs) are increasingly perceived as an emerging threat to terrestrial
environments, but the adverse impacts of NPs on soil fauna and the mechanisms behind …

Simultaneous targeting of peripheral and brain tumors with a therapeutic nanoparticle to disrupt metabolic adaptability at both sites

A Ashokan, S Sarkar, MZ Kamran, B Surnar… - Proceedings of the …, 2024 - pnas.org
Brain metastasis of advanced breast cancer often results in deleterious consequences.
Metastases to the brain lead to significant challenges in treatment options, as the blood …

Nano drug-delivery systems for management of AIDS: liposomes, dendrimers, gold and silver nanoparticles

FD Asl, M Mousazadeh, S Taji, A Bahmani… - …, 2023 - Taylor & Francis
AIDS causes increasing mortality every year. With advancements in nanomedicine, different
nanomaterials (NMs) have been applied to treat AIDS and overcome its limitations. Among …

Engineering advanced nanomedicines against central nervous system diseases

S Shi, H Ren, Y **e, M Yu, Y Chen, L Yang - Materials Today, 2023 - Elsevier
Despite the impressive strides in the research community, numerous obstacles pose marked
challenges in the treatment of central nervous system (CNS) disorders. The limitations of …

Biomaterial strategies for regulating the neuroinflammatory response

AN Galindo, DAF Rubio, MH Hettiaratchi - Materials Advances, 2024 - pubs.rsc.org
Injury and disease in the central nervous system (CNS) can result in a dysregulated
inflammatory environment that inhibits the repair of functional tissue. Biomaterials present a …

[HTML][HTML] Harnessing nanomedicine for modulating microglial states in the central nervous system disorders: challenges and opportunities

H Li, M Guan, NN Zhang, Y Wang, T Liang… - Biomedicine & …, 2024 - Elsevier
Microglia are essential for maintaining homeostasis and responding to pathological events
in the central nervous system (CNS). Their dynamic and multidimensional states in different …

Recent advances, status, and opportunities of magneto-electric nanocarriers for biomedical applications

N Kolishetti, A Vashist, AY Arias, V Atluri, S Dhar… - Molecular aspects of …, 2022 - Elsevier
Magneto-electric (ME) materials with core-shell architecture where the core is made of
magnetic materials have emerged as an attractive nanomaterial due to the coupling of …

Mechanisms and treatments of methamphetamine and HIV-1 co-induced neurotoxicity: a systematic review

L Miao, H Wang, Y Li, J Huang, C Wang… - Frontiers in …, 2024 - frontiersin.org
Combination antiretroviral therapy (cART) has dramatically reduced mortality in people with
human immunodeficiency virus (HIV), but it does not completely eradicate the virus from the …