Fluorine in pharmaceutical industry: fluorine-containing drugs introduced to the market in the last decade (2001–2011)
J Wang, M Sánchez-Roselló, JL Aceña… - Chemical …, 2014 - ACS Publications
1.1. Brief Historical Overview As expected from the fluorine position on the periodic table of
elements, it possesses some extreme properties, in particular, ultimate electronegativity and …
elements, it possesses some extreme properties, in particular, ultimate electronegativity and …
Phthalides and phthalans: synthetic methodologies and their applications in the total synthesis
Small molecule natural products have been the mainstay of research in organic chemistry
since its early development. 1a The established classes of natural products, like alkaloids …
since its early development. 1a The established classes of natural products, like alkaloids …
Chiral 1, 1-diaryl compounds as important pharmacophores
Compounds containing a 1, 1-diaryl motif are numerous, and compounds of this type have
found use as catalysts and molecular building blocks, however, this review focusses solely …
found use as catalysts and molecular building blocks, however, this review focusses solely …
Application of lipases in kinetic resolution of racemates
Lipases have been well established as valuable catalysts in organic synthesis. This review
article focuses on some of the recent developments in the rapidly growing field of lipase …
article focuses on some of the recent developments in the rapidly growing field of lipase …
Trends in lipase-catalyzed asymmetric access to enantiomerically pure/enriched compounds
Over the last few years, there has been a dramatic increase in the number of publications in
the field of lipase-catalyzed reactions performed in common organic solvents, ionic liquids or …
the field of lipase-catalyzed reactions performed in common organic solvents, ionic liquids or …
Lipase-mediated chiral resolution of racemates in organic solvents
Lipase-catalyzed kinetic resolution of racemates is considered to be one of the most
fascinating topics in asymmetric catalysis. This review focuses on some of the recent …
fascinating topics in asymmetric catalysis. This review focuses on some of the recent …
Application of Lipase B from Candida antarctica in the Pharmaceutical Industry
H Wang, Q Zhang, X Yu, J Liang, Y Zhang… - Industrial & …, 2023 - ACS Publications
The use of biocatalysts in pharmaceutical production is an important approach for the
pharmaceutical industry to achieve green manufacturing. Compared to other lipases …
pharmaceutical industry to achieve green manufacturing. Compared to other lipases …
Biocatalytic approaches towards the stereoselective synthesis of vicinal amino alcohols
The global need for clean manufacturing technologies and the management of hazardous
chemicals and waste present new research challenges to both chemistry and biotechnology …
chemicals and waste present new research challenges to both chemistry and biotechnology …
Glutaraldehyde cross-linking of lipases adsorbed on aminated supports in the presence of detergents leads to improved performance
Lipases from Candida rugosa (CRL) and lipase isoforms A and B from Candida antarctica
(CAL-A and CAL-B) were adsorbed on aminated supports in the presence of detergents to …
(CAL-A and CAL-B) were adsorbed on aminated supports in the presence of detergents to …
Catalytic Asymmetric Total Synthesis of (+)‐Chamaecydin and (+)‐Isochamaecydin and their Stereoisomers
YH Zhang, LH Deng, DX Tan… - Angewandte Chemie …, 2025 - Wiley Online Library
A modular approach was developed for the first catalytic asymmetric total syntheses of
naturally occurring C30 terpene quinone methides and their non‐natural stereoisomers …
naturally occurring C30 terpene quinone methides and their non‐natural stereoisomers …