Osteoarthritis (OA) represents a final and common pathway for all major traumatic insults to
synovial joints. OA is the most common form of degenerative joint disease and a major …

Background Intervertebral disc degeneration has an annual worldwide socioeconomic
impact masked as low back pain of over 70 billion euros. This disease has a high …

Intervertebral disc (IVD) degeneration is a challenging clinical problem that urgently
demands viable nucleus pulposus (NP) implant materials. The best suited biomaterial for NP …

Cell-based therapies have shown significant promise in tissue engineering with one key
challenge being the delivery and retention of cells. As a result, significant efforts have been …

Defects of load‐bearing connective tissues such as articular cartilage and intervertebral disc
(IVD) can result from trauma, degenerative, endocrine, or age‐related disease. Current …

Intervertebral disc (IVD) degeneration is one of the major causes of low back pain. As
current clinical treatments are aimed at restoring biomechanical function and providing …

Tissue and organ repair still represents a clinical challenge. Tissue engineering and
regenerative medicine (TERM) is an emerging field focused on the development of …

Disc degeneration is a common disorder. Although the back pain that can develop in
association with this is rarely life-threatening, the annual cost in terms of morbidity, lost …

Regenerating chondral and osteochondral injuries is a main challenge in orthopedics.
Some therapeutic strategies such as joint preservation operations, non-operative …

Defects of load-bearing connective tissues such as articular cartilage, often result from
trauma, degenerative or age-related disease. Osteoarthritis (OA) presents a major clinical …