Therapeutic supramolecular polymers: Designs and applications

H Wang, J Mills, B Sun, H Cui - Progress in polymer science, 2024 - Elsevier
The self-assembly of low-molecular-weight building motifs into supramolecular polymers
has unlocked a new realm of materials with distinct properties and tremendous potential for …

Self-assembly of peptide nanomaterials at biointerfaces: molecular design and biomedical applications

XY Guo, L Yi, J Yang, HW An, ZX Yang… - Chemical …, 2024 - pubs.rsc.org
Self-assembly is an important strategy for constructing ordered structures and complex
functions in nature. Based on this, people can imitate nature and artificially construct …

A matter of charge: Electrostatically tuned coassembly of amphiphilic peptides

E Arad, T Levi, G Yosefi, I Kass, I Cohen‐Erez… - Small, 2024 - Wiley Online Library
Coassembly of peptide biomaterials offers a compelling avenue to broaden the spectrum of
hierarchically ordered supramolecular nanoscale structures that may be relevant for …

Dynamic Peptide Nanoframework-Guided Protein Coassembly: Advancing Adhesion Performance with Hierarchical Structures

Y Zhou, R Chang, Z Yang, Q Guo, M Wang… - Journal of the …, 2025 - ACS Publications
Hierarchical structures are essential in natural adhesion systems. Replicating these in
synthetic adhesives is challenging due to intricate molecular mechanisms and multiscale …

A Mn2+‐Assisted Nanofiber‐Hydrogel Adjuvant for Simultaneous Enhancement of Humoral and Cellular Immune Responses

H Jia, J Lin, D Wang, X Lv, Q Wang… - Advanced Functional …, 2024 - Wiley Online Library
Limited ability to elicit cellular immune responses has restricted the effectiveness of
conventional adjuvants in the context of cancers. Recent advancements in innate immune …

Context-Dependent Heterotypic Assemblies of Intrinsically Disordered Peptides

Y Qiao, A Zia, G Wu, Z Liu, J Guo, M Chu… - Journal of the …, 2025 - ACS Publications
Despite their critical role in context-dependent interactions for protein functions, intrinsically
disordered regions (IDRs) are often overlooked for designing peptide assemblies. Here, we …

3D Cryo-Electron Microscopy Reveals the Structure of a 3-Fluorenylmethyloxycarbonyl Zipper Motif Ensuring the Self-Assembly of Tripeptide Nanofibers

A Bigo-Simon, LF Estrozi, A Chaumont… - ACS …, 2024 - ACS Publications
Short peptide-based supramolecular hydrogels appeared as highly interesting materials for
applications in many fields. The optimization of their properties relies mainly on the design of …

Proteins for Hyperelastic Materials

R Su, C Ma, B Han, H Zhang, K Liu - Small, 2025 - Wiley Online Library
Meticulous engineering and the yielded hyperelastic performance of structural proteins
represent a new frontier in develo** next‐generation functional biomaterials. These …

Artificial Peptide‐Protein Necrosomes Promote Cell Death

RC Guo, N Wang, W Wang, Z Zhang… - Angewandte Chemie …, 2023 - Wiley Online Library
The presence of disordered region or large interacting surface within proteins significantly
challenges the development of targeted drugs, commonly known as the “undruggable” …

Two-Step Chirality Transfer to Twisted Assemblies: Synergistic Interplay of Chiral and Aggregation Interactions

SJ Li, YW Sun, ZW Li - ACS nano, 2024 - ACS Publications
Chirality plays a pivotal role in both the origin of life and the self-assembly of materials.
However, the governing principles behind chirality transfer in hierarchical self-assembly …