Therapeutic supramolecular polymers: Designs and applications
The self-assembly of low-molecular-weight building motifs into supramolecular polymers
has unlocked a new realm of materials with distinct properties and tremendous potential for …
has unlocked a new realm of materials with distinct properties and tremendous potential for …
Self-assembly of peptide nanomaterials at biointerfaces: molecular design and biomedical applications
XY Guo, L Yi, J Yang, HW An, ZX Yang… - Chemical …, 2024 - pubs.rsc.org
Self-assembly is an important strategy for constructing ordered structures and complex
functions in nature. Based on this, people can imitate nature and artificially construct …
functions in nature. Based on this, people can imitate nature and artificially construct …
A matter of charge: Electrostatically tuned coassembly of amphiphilic peptides
Coassembly of peptide biomaterials offers a compelling avenue to broaden the spectrum of
hierarchically ordered supramolecular nanoscale structures that may be relevant for …
hierarchically ordered supramolecular nanoscale structures that may be relevant for …
Dynamic Peptide Nanoframework-Guided Protein Coassembly: Advancing Adhesion Performance with Hierarchical Structures
Y Zhou, R Chang, Z Yang, Q Guo, M Wang… - Journal of the …, 2025 - ACS Publications
Hierarchical structures are essential in natural adhesion systems. Replicating these in
synthetic adhesives is challenging due to intricate molecular mechanisms and multiscale …
synthetic adhesives is challenging due to intricate molecular mechanisms and multiscale …
A Mn2+‐Assisted Nanofiber‐Hydrogel Adjuvant for Simultaneous Enhancement of Humoral and Cellular Immune Responses
H Jia, J Lin, D Wang, X Lv, Q Wang… - Advanced Functional …, 2024 - Wiley Online Library
Limited ability to elicit cellular immune responses has restricted the effectiveness of
conventional adjuvants in the context of cancers. Recent advancements in innate immune …
conventional adjuvants in the context of cancers. Recent advancements in innate immune …
Context-Dependent Heterotypic Assemblies of Intrinsically Disordered Peptides
Despite their critical role in context-dependent interactions for protein functions, intrinsically
disordered regions (IDRs) are often overlooked for designing peptide assemblies. Here, we …
disordered regions (IDRs) are often overlooked for designing peptide assemblies. Here, we …
3D Cryo-Electron Microscopy Reveals the Structure of a 3-Fluorenylmethyloxycarbonyl Zipper Motif Ensuring the Self-Assembly of Tripeptide Nanofibers
Short peptide-based supramolecular hydrogels appeared as highly interesting materials for
applications in many fields. The optimization of their properties relies mainly on the design of …
applications in many fields. The optimization of their properties relies mainly on the design of …
Proteins for Hyperelastic Materials
R Su, C Ma, B Han, H Zhang, K Liu - Small, 2025 - Wiley Online Library
Meticulous engineering and the yielded hyperelastic performance of structural proteins
represent a new frontier in develo** next‐generation functional biomaterials. These …
represent a new frontier in develo** next‐generation functional biomaterials. These …
Artificial Peptide‐Protein Necrosomes Promote Cell Death
RC Guo, N Wang, W Wang, Z Zhang… - Angewandte Chemie …, 2023 - Wiley Online Library
The presence of disordered region or large interacting surface within proteins significantly
challenges the development of targeted drugs, commonly known as the “undruggable” …
challenges the development of targeted drugs, commonly known as the “undruggable” …
Two-Step Chirality Transfer to Twisted Assemblies: Synergistic Interplay of Chiral and Aggregation Interactions
SJ Li, YW Sun, ZW Li - ACS nano, 2024 - ACS Publications
Chirality plays a pivotal role in both the origin of life and the self-assembly of materials.
However, the governing principles behind chirality transfer in hierarchical self-assembly …
However, the governing principles behind chirality transfer in hierarchical self-assembly …