Summary The interleukin‐1 (IL‐1) family of cytokines and receptors is unique in immunology
because the IL‐1 family and Toll‐like receptor (TLR) families share similar functions. More …

Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …

The fungal cell wall is essential for growth and survival, and is a key target for antifungal
drugs and the immune system. The cell wall must be robust but flexible, protective and …

Sepsis—which is a severe life-threatening infection with organ dysfunction—initiates a
complex interplay of host pro-inflammatory and anti-inflammatory processes. Sepsis can be …

Simple and complex carbohydrates (glycans) have long been known to play major
metabolic, structural and physical roles in biological systems. Targeted microbial binding to …

Oral candidiasis, commonly referred to as “thrush,” is an opportunistic fungal infection that
commonly affects the oral mucosa. The main causative agent, Candida albicans, is a highly …

Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Invasive infection caused by Candida species is a condition associated with medical
progress. It is a common health care–associated infection (HAI), and is widely recognized as …

The immune system is coordinated by an intricate network of stimulatory and inhibitory
circuits that regulate host responses against endogenous and exogenous insults. Disruption …

The surveillance and elimination of fungal pathogens rely heavily on the sentinel behaviour
of phagocytic cells of the innate immune system, especially macrophages and neutrophils …