Roles of Porphyromonas gingivalis and its virulence factors in periodontitis

W Xu, W Zhou, H Wang, S Liang - Advances in protein chemistry and …, 2020 - Elsevier
Periodontitis is an infection-driven inflammatory disease, which is characterized by gingival
inflammation and bone loss. Periodontitis is associated with various systemic diseases …

Basic biology and role of interleukin‐17 in immunity and inflammation

C Zenobia, G Hajishengallis - Periodontology 2000, 2015 - Wiley Online Library
Interleukin‐17 (also known as interleukin‐17A) is a key cytokine that links T‐cell activation to
neutrophil mobilization and activation. As such, interleukin‐17 can mediate protective innate …

Revisiting the Page & Schroeder model: the good, the bad and the unknowns in the periodontal host response 40 years later

G Hajishengallis, JM Korostoff - Periodontology 2000, 2017 - Wiley Online Library
In their classic 1976 paper, Page & Schroeder described the histopathologic events and the
types of myeloid cells and lymphocytes involved in the initiation and progression of …

The periodontal war: microbes and immunity

JL Ebersole, D Dawson III, P Emecen‐Huja… - Periodontology …, 2017 - Wiley Online Library
Maintenance of periodontal health or transition to a periodontal lesion reflects the
continuous and ongoing battle between the vast microbial ecology in the oral cavity and the …

IL‐17: overview and role in oral immunity and microbiome

L Abusleme, NM Moutsopoulos - Oral diseases, 2017 - Wiley Online Library
Interleukin‐17 (IL‐17) is a multifaceted cytokine with diverse roles in both immune protection
and also immunopathology. IL‐17 has a well‐recognized role in immune surveillance at …

Association between Porphyromonas Gingivalis and systemic diseases: Focus on T cells-mediated adaptive immunity

C Li, R Yu, Y Ding - Frontiers in cellular and infection microbiology, 2022 - frontiersin.org
The association between periodontal disease and systemic disease has become a research
hotspot. Porphyromonas gingivalis (P. gingivalis), a crucial periodontal pathogen, affects the …

The function of dendritic cells in modulating the host response

L Song, G Dong, L Guo… - Molecular oral …, 2018 - Wiley Online Library
Dendritic cells (DC s) are antigen‐presenting cells that capture, process, and present
antigens to lymphocytes to initiate and regulate the adaptive immune response. DC s detect …

The presence, function and regulation of IL‐17 and Th17 cells in periodontitis

WC Cheng, FJ Hughes… - Journal of clinical …, 2014 - Wiley Online Library
Periodontitis (PD) is a chronic inflammatory disease characterised by tissue inflammation
and destruction of the associated alveolar bone. It is caused by the colonisation of the …

Effect of probiotic Lactobacillus rhamnosus by-products on gingival epithelial cells challenged with Porphyromonas gingivalis

GC Vale, MPA Mayer - Archives of oral biology, 2021 - Elsevier
Objective Probiotics are usually given as living cells, but their effects may be also achieved
by postbiotics. We hypothesized that probiotics products (spent media and lysate) altered …

The role of acquired host immunity in periodontal diseases

DF Kinane, DF Lappin, S Culshaw - Periodontology 2000, 2024 - Wiley Online Library
The aim of this narrative review is to relate the contribution of European researchers to the
complex topic of the host immune system in periodontal disease, focusing on acquired …