Chronic endometritis and infertility

HJ Park, YS Kim, TK Yoon… - Clinical and experimental …, 2016 - pmc.ncbi.nlm.nih.gov
Chronic endometritis (CE) is a condition involving the breakdown of the peaceful co-
existence between microorganisms and the host immune system in the endometrium. A …

The preterm parturition syndrome

R Romero, J Espinoza, JP Kusanovic… - … Journal of Obstetrics …, 2006 - Wiley Online Library
The implicit paradigm that has governed the study and clinical management of preterm
labour is that term and preterm parturition are the same processes, except for the gestational …

Single cell transcriptional signatures of the human placenta in term and preterm parturition

R Pique-Regi, R Romero, AL Tarca, ED Sendler, Y Xu… - Elife, 2019 - elifesciences.org
More than 135 million births occur each year; yet, the molecular underpinnings of human
parturition in gestational tissues, and in particular the placenta, are still poorly understood …

The role of inflammation and infection in preterm birth

R Romero, J Espinoza, LF Gonçalves… - Seminars in …, 2007 - thieme-connect.com
Inflammation has been implicated in the mechanisms responsible for preterm and term
parturition, as well as fetal injury. Out of all of the suspected causes of preterm labor and …

Intrauterine infection and preterm labor

V Agrawal, E Hirsch - Seminars in Fetal and Neonatal Medicine, 2012 - Elsevier
Preterm labor is defined as labor that begins before 37 completed weeks of pregnancy.
More than 12% of infants born in the USA are preterm. At least 40% of preterm births are …

Inflammation in preterm and term labour and delivery

R Romero, J Espinoza, LF Gonçalves… - Seminars in Fetal and …, 2006 - Elsevier
Inflammation has been implicated in the mechanisms responsible for preterm and term
parturition, as well as fetal injury. Out of all of the suspected causes of preterm labour and …

Mechanisms of immune regulation by the placenta: role of type I interferon and Interferon‐stimulated genes signaling during pregnancy

J Ding, A Maxwell, N Adzibolosu, A Hu… - Immunological …, 2022 - Wiley Online Library
Pregnancy is a unique condition where the maternal immune system is continuously
adapting in response to the stages of fetal development and signals from the environment …

The fetal inflammatory response syndrome

F Gotsch, R Romero, JP Kusanovic… - Clinical obstetrics and …, 2007 - journals.lww.com
The fetal inflammatory response syndrome (FIRS) is a condition characterized by systemic
inflammation and an elevation of fetal plasma interleukin-6. This syndrome has been …

[HTML][HTML] Clinical chorioamnionitis at term I: microbiology of the amniotic cavity using cultivation and molecular techniques

R Romero, J Miranda, JP Kusanovic… - Journal of perinatal …, 2015 - degruyter.com
Introduction: The objectives of this study were: 1) to determine the amniotic fluid (AF)
microbiology of patients with the diagnosis of clinical chorioamnionitis at term using both …

Insight into TLR4-mediated immunomodulation in normal pregnancy and related disorders

P Firmal, VK Shah, S Chattopadhyay - Frontiers in immunology, 2020 - frontiersin.org
Unlike organ transplants where an immunosuppressive environment is required, a
successful pregnancy involves an extremely robust, dynamic, and responsive maternal …