Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative
DP Veitch, MW Weiner, PS Aisen, LA Beckett… - Alzheimer's & …, 2019 - Elsevier
Introduction The overall goal of the Alzheimer's Disease Neuroimaging Initiative (ADNI) is to
validate biomarkers for Alzheimer's disease (AD) clinical trials. ADNI is a multisite …
validate biomarkers for Alzheimer's disease (AD) clinical trials. ADNI is a multisite …
Sleep quality and aging: a systematic review on healthy older people, mild cognitive impairment and Alzheimer's disease
Aging is characterized by changes in the structure and quality of sleep. When the alterations
in sleep become substantial, they can generate or accelerate cognitive decline, even in the …
in sleep become substantial, they can generate or accelerate cognitive decline, even in the …
Mild behavioral impairment is associated with atrophy of entorhinal cortex and hippocampus in a memory clinic cohort
V Matuskova, Z Ismail, T Nikolai, H Markova… - Frontiers in aging …, 2021 - frontiersin.org
Objectives Mild behavioral impairment (MBI) is a syndrome describing late-onset persistent
neuropsychiatric symptoms (NPS) in non-demented older adults. Few studies to date have …
neuropsychiatric symptoms (NPS) in non-demented older adults. Few studies to date have …
Mild behavioral impairment is associated with β‐amyloid but not tau or neurodegeneration in cognitively intact elderly individuals
Introduction Mild behavioral impairment (MBI) is characterized by the emergence of
neuropsychiatric symptoms in elderly persons. Here, we examine the associations between …
neuropsychiatric symptoms in elderly persons. Here, we examine the associations between …
Affective and emotional dysregulation as pre-dementia risk markers: exploring the mild behavioral impairment symptoms of depression, anxiety, irritability, and …
Z Ismail, J Gatchel, DR Bateman… - International …, 2018 - cambridge.org
Background: Affective and emotional symptoms such as depression, anxiety, euphoria, and
irritability are common neuropsychiatric symptoms (NPS) in pre-dementia and cognitively …
irritability are common neuropsychiatric symptoms (NPS) in pre-dementia and cognitively …
Classification of Alzheimer's disease and frontotemporal dementia using routine clinical and cognitive measures across multicentric underrepresented samples: a …
MA Maito, H Santamaría-García… - The Lancet Regional …, 2023 - thelancet.com
Background Global brain health initiatives call for improving methods for the diagnosis of
Alzheimer's disease (AD) and frontotemporal dementia (FTD) in underrepresented …
Alzheimer's disease (AD) and frontotemporal dementia (FTD) in underrepresented …
Using machine learning to predict dementia from neuropsychiatric symptom and neuroimaging data
Background: Machine learning (ML) is a promising technique for patient-specific prediction
of mild cognitive impairment (MCI) and dementia development. Neuropsychiatric symptoms …
of mild cognitive impairment (MCI) and dementia development. Neuropsychiatric symptoms …
Assessing mild behavioral impairment with the mild behavioral impairment-checklist in people with mild cognitive impairment
Background: Neuropsychiatric symptoms (NPS) are non-cognitive, behavioral, or psychiatric
symptoms, common in mild cognitive impairment (MCI) and associated with a higher risk of …
symptoms, common in mild cognitive impairment (MCI) and associated with a higher risk of …
The implications of different approaches to define AT (N) in Alzheimer disease
N Mattsson-Carlgren, A Leuzy, S Janelidze… - Neurology, 2020 - AAN Enterprises
Objective To compare different β-amyloid (Aβ), tau, and neurodegeneration (AT [N]) variants
within the Swedish BioFINDER studies. Methods A total of 490 participants were classified …
within the Swedish BioFINDER studies. Methods A total of 490 participants were classified …
Neural correlates of the impulse dyscontrol domain of mild behavioral impairment
S Gill, M Wang, P Mouches… - … Journal of Geriatric …, 2021 - Wiley Online Library
Objectives Agitation and aggression are common in dementia and pre‐dementia. The
dementia risk syndrome mild behavioral impairment (MBI) includes these symptoms in the …
dementia risk syndrome mild behavioral impairment (MBI) includes these symptoms in the …