Growing up in a changing world: environmental regulation of development in insects

CK Mirth, TE Saunders… - Annual Review of …, 2021 - annualreviews.org
All organisms are exposed to changes in their environment throughout their life cycle. When
confronted with these changes, they adjust their development and physiology to ensure that …

Butterfly eyespots evolved via cooption of an ancestral gene-regulatory network that also patterns antennae, legs, and wings

SN Murugesan, H Connahs… - Proceedings of the …, 2022 - National Acad Sciences
Butterfly eyespots are beautiful novel traits with an unknown developmental origin. Here we
show that eyespots likely originated via cooption of parts of an ancestral appendage gene …

Spatial and temporal regulation of Wnt signaling pathway members in the development of butterfly wing patterns

TD Banerjee, SN Murugesan, H Connahs… - Science …, 2023 - science.org
Wnt signaling members are involved in the differentiation of cells associated with eyespot
and band color patterns on the wings of butterflies, but the identity and spatio-temporal …

The Developmental Origin of Novel Complex Morphological Traits in Lepidoptera

A Monteiro, SN Murugesan, A Prakash… - Annual Review of …, 2025 - annualreviews.org
Novel traits in the order Lepidoptera include prolegs in the abdomen of larvae, scales, and
eyespot and band color patterns in the wings of adults. We review recent work that …

Frizzled2 receives WntA signaling during butterfly wing pattern formation

JJ Hanly, LS Loh, A Mazo-Vargas… - …, 2023 - journals.biologists.com
Butterfly color patterns provide visible and biodiverse phenotypic readouts of the patterning
processes. Although the secreted ligand WntA has been shown to instruct the color pattern …

[HTML][HTML] Antibody-mediated protein knockdown reveals Distal-less functions for eyespots and parafocal elements in butterfly wing color pattern development

Y Nakazato, JM Otaki - Cells, 2024 - pmc.ncbi.nlm.nih.gov
One of the important genes for eyespot development in butterfly wings is Distal-less. Its
function has been evaluated via several methods, including CRISPR/Cas9 genome editing …

A Transcriptomic Atlas Underlying Developmental Plasticity of Seasonal Forms of Bicyclus anynana Butterflies

S Tian, A Monteiro - Molecular biology and evolution, 2022 - academic.oup.com
Organisms residing in regions with alternating seasons often develop different phenotypes,
or forms, in each season. These forms are often adaptations to each season and result from …

[HTML][HTML] Socket array irregularities and wing membrane distortions at the eyespot foci of butterfly wings suggest mechanical signals for color pattern determination

Y Nakazato, JM Otaki - Insects, 2024 - mdpi.com
Simple Summary Eyespot foci on butterfly wings function as organizers for eyespot color
patterns during development. Here, we microscopically examined the scales, sockets, and …

Hox genes are essential for the development of eyespots in Bicyclus anynana butterflies

Y Matsuoka, A Monteiro - Genetics, 2021 - academic.oup.com
The eyespot patterns found on the wings of nymphalid butterflies are novel traits that
originated first in hindwings and subsequently in forewings, suggesting that eyespot …

Cis-regulatory modes of Ultrabithorax inactivation in butterfly forewings

A Tendolkar, A Mazo-Vargas, L Livraghi, JJ Hanly… - ELife, 2024 - elifesciences.org
Hox gene clusters encode transcription factors that drive regional specialization during
animal development: for example the Hox factor Ubx is expressed in the insect metathoracic …