Prediction of RNA subcellular localization: learning from heterogeneous data sources

AF Savulescu, E Bouilhol, N Beaume, M Nikolski - Iscience, 2021 - cell.com
RNA subcellular localization has recently emerged as a widespread phenomenon, which
may apply to the majority of RNAs. The two main sources of data for characterization of RNA …

Quantifying F-actin patches in single melanoma cells using total-internal reflection fluorescence microscopy

E Sheykhi, B Shojaedin-Givi, B Sajad… - Scientific Reports, 2022 - nature.com
Total-internal reflection fluorescence (TIRF) microscope is a unique technique for selective
excitation of only those fluorophore molecules in a cellular environment, which are located …

Unsupervised discovery of dynamic cell phenotypic states from transmitted light movies

P Nguyen, S Chien, J Dai, RJ Monnat Jr… - PLoS computational …, 2021 - journals.plos.org
Identification of cell phenotypic states within heterogeneous populations, along with
elucidation of their switching dynamics, is a central challenge in modern biology …

A review of computational modeling, machine learning and image analysis in cancer metastasis dynamics

SU Hirway, SH Weinberg - Computational and Systems …, 2023 - Wiley Online Library
Cancer is a life‐threatening process that stems from genetic mutations in cells, which leads
to the formation of tumors, and is a major cause of deaths in the United States, with …

Immunofluorescence image feature analysis and phenotype scoring pipeline for distinguishing epithelial–mesenchymal transition

SU Hirway, NT Hassan, M Sofroniou… - Microscopy and …, 2021 - academic.oup.com
Epithelial–mesenchymal transition (EMT) is an essential biological process, also implicated
in pathological settings such as cancer metastasis, in which epithelial cells transdifferentiate …

Automated segmentation of cells in phase contrast optical microscopy time series images

RC Binici, U Şahin, A Ayanzadeh… - 2019 Medical …, 2019 - ieeexplore.ieee.org
Phase contrast optical microscopy is a preferred imaging technique for live-cell, temporal
analysis. Segmentation of cells from time series data acquired with this technique is a labor …

Deep learning based segmentation pipeline for label-free phase-contrast microscopy images

A Ayanzadeh, ÖY Özuysal, DP Okvur… - 2020 28th Signal …, 2020 - ieeexplore.ieee.org
The segmentation of cells is necessary for biologists in the morphological statistics for
quantitative and qualitative analysis in Phase-contrast Microscopy (PCM) images. In this …

Novel imaging approaches to decipher T cell decision-making

S Webster - 2024 - unsworks.unsw.edu.au
Microvilli are exoplasmic protrusions of the T cell plasma membrane which are functionally
critical for T cell motility and have now also been implicated as determinants of signalling …

Morphological Cell Classification under Weak Supervision: A Learning from Label Proportions Approach

T Jiao - 2025 - studenttheses.uu.nl
Classification of cells is an important field for biology and pathology research, and there
have been many effective models integrating it with machine learning techniques. In the …

A Machine Learning Based Diagnostic Study of Chronic Liver Disease Using Staining Techniques

Y Yu - 2020 - search.proquest.com
This thesis described the study of investigation for machine learning-based classification
models for chronic liver diseases (focusing on two main histological patterns: liver fibrosis …