Since the emergence of regenerative medicine and tissue engineering more than half a
century ago, one obstacle has persisted: the in vitro creation of large-scale vascular tissue (> …

Bioreactor technology is vital for tissue engineering. Usually, bioreactors are used to provide
a tissue‐specific physiological in vitro environment during tissue maturation. In addition to …

Biological activity can be added to synthetic scaffolds by incorporating functional peptide
sequences that provide enzyme-mediated degradation sites, facilitate cellular adhesion or …

Local skin cancer recurrence occurs in∼ 12% of the patients post-surgery due to persistent
growth of residual cancer cells. Wound infection is another significant complication following …

Despite the efforts devoted to drug discovery and development, the number of new drug
approvals have been decreasing. Specifically, cardiovascular developments have been …

Articular cartilage (AC) is the weight-bearing tissue in diarthroses. It lacks the capacity for
self-healing once there are injuries or diseases due to its avascularity. With the development …

Fibroblasts as many other cells are known to form, contract, and remodel the extracellular
matrix (ECM). The presented study aims to gain an insight into how mechanical boundary …

Osteoporosis is a polygenetic, environmentally modifiable disease, which precipitates into
fragility fractures of vertebrae, hip and radius and also confers a high risk of fractures in …

Background: Microfracture of focal chondral defects often produces fibrocartilage, which
inconsistently integrates with the surrounding native tissue and possesses inferior …

Cardiovascular diseases remain a leading cause of mortality globally, with atherosclerosis
representing a significant pathological means, often leading to myocardial infarction …