Propargylamines are a versatile class of compounds which find broad application in many
fields of chemistry. This review aims to describe the different strategies developed so far for …

Abstract “Green chemistry” and sustainable catalysis are increasingly attracting significant
attention, in both industry and academia. Multicomponent reactions aim towards “greener” …

A highly enantioselective synthesis of trisubstituted allenes has been achieved through Cu
(I)-catalyzed cross-coupling of aryldiazoalkanes and terminal alkynes with chiral …

Propargylamines are a class of compounds with many pharmaceutical and biological
properties. A green approach to synthesize such compounds is very relevant. This review …

Tetrasubstituted propargylamines comprise a unique class of highly useful compounds,
which can be accessed through the multicomponent coupling between ketones, amines …

Herein, we report a catalytic system based on the earth‐abundant manganese for the
ketone, amine, alkyne (KA2) reaction. The efficiency of manganese manifests at relatively …

Chiral allenes are highly valuable as versatile synthetic intermediates and core skeletons of
various functional organic molecules. Despite marked recent advances, the straightforward …

Carboxylic acids are widely found in natural products and bioactive molecules and have
served as raw material compounds in industry. We now report the first example of copper (I) …

A novel and selective cascade reaction of primary amines and alkynes for the synthesis of
the corresponding secondary propargylamines is described. This protocol proceeds with a …

A straightforward, user-friendly, efficient protocol for the one pot, ZnI2-catalyzed allenylation
of terminal alkynes with pyrrolidine and ketones, toward trisubstituted allenes, is described …