Seasonal and pandemic influenza are the two faces of respiratory infections caused by
influenza viruses in humans. As seasonal influenza occurs on an annual basis, the …

Most people exposed to a new flu virus do not notice any symptoms. A small minority
develops critical illness. Some of this extremely broad variation in susceptibility is explained …

Zoonotic avian influenza A virus (IAV) infections are rare. Sustained transmission of these
IAVs between humans has not been observed, suggesting a role for host genes. We used …

The genetic predisposition to severe A (H1N1) 2009 (A [H1N1] pdm09) influenza was
evaluated in 409 patients, including 162 cases with severe infection and 247 controls with …

Influenza viruses continue to be a major global health threat. Severity and clinical outcome
of influenza disease is determined by both viral and host factors. Viral factors have long …

Galectins are a large family of carbohydrate binding proteins with members in nearly every
lineage of multicellular life. Through tandem and en-mass genome duplications, over 15 …

Abstract The novel coronavirus (2019-nCoV) has recently emerged, causing COVID-19
outbreaks and significant societal/global disruption. Importantly, COVID-19 infection …

Influenza is a global challenge, and future pandemics of influenza are inevitable. One of the
lessons learned from past pandemics is that all pandemic influenza viruses characterized to …

Different families of endogenous lectins use complementary defense strategies against
pathogens. They may recognize non-self glycans typically found on pathogens and/or host …

Influenza viruses cause seasonal epidemics and sporadic pandemics in humans. The
virus's ability to change its antigenic nature through mutation and recombination, and the …