Computational models in cardiology
The treatment of individual patients in cardiology practice increasingly relies on advanced
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …
Molecular and cellular mechanisms of atrial fibrosis in atrial fibrillation
S Nattel - JACC: Clinical Electrophysiology, 2017 - jacc.org
Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. Atrial fibrosis has
emerged as an important pathophysiological contributor and has been linked to AF …
emerged as an important pathophysiological contributor and has been linked to AF …
Computationally guided personalized targeted ablation of persistent atrial fibrillation
Atrial fibrillation (AF)—the most common arrhythmia—significantly increases the risk of
stroke and heart failure. Although catheter ablation can restore normal heart rhythms …
stroke and heart failure. Although catheter ablation can restore normal heart rhythms …
The clinical profile and pathophysiology of atrial fibrillation: relationships among clinical features, epidemiology, and mechanisms
Atrial fibrillation (AF) is the most common arrhythmia (estimated lifetime risk, 22%–26%). The
aim of this article is to review the clinical epidemiological features of AF and to relate them to …
aim of this article is to review the clinical epidemiological features of AF and to relate them to …
Cardiac fibrosis in patients with atrial fibrillation: mechanisms and clinical implications
Atrial fibrillation (AF) is associated with structural, electrical, and contractile remodeling of
the atria. Development and progression of atrial fibrosis is the hallmark of structural …
the atria. Development and progression of atrial fibrosis is the hallmark of structural …
Atrial remodeling and atrial fibrillation: recent advances and translational perspectives
S Nattel, M Harada - Journal of the American College of Cardiology, 2014 - jacc.org
Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice. AF and its
complications are responsible for important population morbidity and mortality. Presently …
complications are responsible for important population morbidity and mortality. Presently …
Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression
Atrial fibrillation (AF) is the most common clinically relevant arrhythmia and is associated
with increased morbidity and mortality. The incidence of AF is expected to continue to rise …
with increased morbidity and mortality. The incidence of AF is expected to continue to rise …
Patient-derived models link re-entrant driver localization in atrial fibrillation to fibrosis spatial pattern
Aims The mechanisms underlying persistent atrial fibrillation (AF) in patients with atrial
fibrosis are poorly understood. The goal of this study was to use patient-derived atrial …
fibrosis are poorly understood. The goal of this study was to use patient-derived atrial …
Efficacy of left atrial voltage‐based catheter ablation of persistent atrial fibrillation
T Yamaguchi, T Tsuchiya, S Nakahara… - Journal of …, 2016 - Wiley Online Library
Low Voltage‐Based Ablation for Atrial Fibrillation Background Low‐voltage zones (LVZs)
represent fibrotic tissue and are substrates for atrial fibrillation (AF). We hypothesized that …
represent fibrotic tissue and are substrates for atrial fibrillation (AF). We hypothesized that …
[HTML][HTML] Computational modeling of cardiac electrophysiology and arrhythmogenesis: toward clinical translation
The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …
components across multiple spatial (from ion channel to organ) and temporal (from …