A network-biology perspective of microRNA function and dysfunction in cancer
MicroRNAs (miRNAs) participate in most aspects of cellular differentiation and homeostasis,
and consequently have roles in many pathologies, including cancer. These small non …
and consequently have roles in many pathologies, including cancer. These small non …
Non-coding RNAs and epithelial mesenchymal transition in cancer: molecular mechanisms and clinical implications
Epithelial-mesenchymal transition (EMT) is a fundamental process for embryonic
development during which epithelial cells acquire mesenchymal characteristics, and the …
development during which epithelial cells acquire mesenchymal characteristics, and the …
Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA)
Background Docosahexaenoic acid (DHA) is a natural compound with anticancer and anti-
angiogenesis activity that is currently under investigation as both a preventative agent and …
angiogenesis activity that is currently under investigation as both a preventative agent and …
miR-23b-3p regulates the chemoresistance of gastric cancer cells by targeting ATG12 and HMGB2
Y An, Z Zhang, Y Shang, X Jiang, J Dong, P Yu… - Cell Death & …, 2015 - nature.com
Chemotherapy is an important treatment modality for gastric cancer (GC); however, it usually
fails because of drug resistance, especially multidrug resistance (MDR). Previously, we …
fails because of drug resistance, especially multidrug resistance (MDR). Previously, we …
[HTML][HTML] Phytoestrogens and breast cancer: In vitro anticancer activities of isoflavones, lignans, coumestans, stilbenes and their analogs and derivatives
P Basu, C Maier - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Breast cancer is one of the leading causes of cancer-related morbidity and mortality among
women worldwide. Phytoestrogens, plant-derived polyphenols that structurally and …
women worldwide. Phytoestrogens, plant-derived polyphenols that structurally and …
Non-muscle myosin II in disease: mechanisms and therapeutic opportunities
KA Newell-Litwa, R Horwitz… - Disease models & …, 2015 - journals.biologists.com
The actin motor protein non-muscle myosin II (NMII) acts as a master regulator of cell
morphology, with a role in several essential cellular processes, including cell migration and …
morphology, with a role in several essential cellular processes, including cell migration and …
miR-23b and miR-27b are oncogenic microRNAs in breast cancer: evidence from a CRISPR/Cas9 deletion study
Background Altered expression of microRNAs (miRNAs) is known to contribute to cancer
progression. miR-23b and miR-27b, encoded within the same miRNA cluster, are reported …
progression. miR-23b and miR-27b, encoded within the same miRNA cluster, are reported …
microRNAs as cancer therapeutics: A step closer to clinical application
TC Ivkovic, G Voss, H Cornella, Y Ceder - Cancer letters, 2017 - Elsevier
During the last decades, basic and translational research has enabled great improvements
in the clinical management of cancer. However, scarcity of complete remission and many …
in the clinical management of cancer. However, scarcity of complete remission and many …
Molecular links between central obesity and breast cancer
Worldwide, breast cancer (BC) is the most common malignancy in women, in regard to
incidence and mortality. In recent years, the negative role of obesity during BC development …
incidence and mortality. In recent years, the negative role of obesity during BC development …
The emerging role of miRNA clusters in breast cancer progression
Micro RNAs (miRNAs) are small non-coding RNAs that are essential for regulation of gene
expression of the target genes. Large number of miRNAs are organized into defined units …
expression of the target genes. Large number of miRNAs are organized into defined units …