Alzheimer's disease is the most common form of age-related neurodegenerative dementia.
The disease is characterised by the presence of plaques in the cerebral cortex. The major …

This tutorial review covers the chemistry of artificial receptors designed to recognize the
pertechnetate and perrhenate anions. It focuses on the molecular features that give rise to …

Bifunctional chelates offer a general approach for the linking of radioactive metal cations to
macromolecules. In the specific case of 99mTc, a variety of technologies have been …

Fibroblast activation protein (FAP) is expressed in the microenvironment of most human
epithelial tumors. 68Ga-labeled FAP inhibitors based on the cyanopyrrolidine structure …

Background Prostate-specific membrane antigen (PSMA) is highly over-expressed in
advanced prostate cancers. 68 Ga-labeled PSMA inhibitors (iPSMA) are currently used for …

Protein aggregation has been widely implicated in neurodegenerative diseases such as
Alzheimer's disease, frontotemporal dementia, Parkinson's disease, and Huntington …

Parallel studies of the preparation of Re and 99mTc agents aid in interpreting the nature of
tracer 99mTc radiopharmaceuticals. Aqueous solutions of the fac-[99mTc (CO) 3 (H2O) 3]+ …

INTRODUCTION: The rekindled interest in the 68Ga generator as an attractive positron
emission tomography generator system has led us and others to investigate novel chelate …

Monosubstituted [M (N) Cl2 (POP)][M= Tc, 1; Re, 2] and [M (N) Cl2 (PNP)][M= Tc, 3; Re, 4]
complexes were prepared by reaction of the precursors [M (N) Cl4]-and [M (N) Cl2 (PPh3) …

The most common form of dementia is Alzheimer's disease, a progressive
neurodegenerative disease that leads to synaptic failure and neuronal death. This review …