RNA binding proteins in extracellular vesicles and their potential value for cancer diagnosis and treatment

W Sun, H Cui, T Xu, J Yue, J Liang… - International …, 2023 - spandidos-publications.com
Extracellular vesicles (EVs) are spherical bilayer membrane vesicles released by cells into
extracellular spaces and body fluids, including plasma and synovial fluid. EV cargo …

Exosome theranostics: comparative analysis of P body and exosome proteins and their mutations for clinical applications

G Satheeshan, AK Si, J Rutta, T Venkatesh - Functional & Integrative …, 2024 - Springer
Exosomes are lipid-bilayered vesicles, originating from early endosomes that capture
cellular proteins and genetic materials to form multi-vesicular bodies. These exosomes are …

Neonatal enteroids absorb extracellular vesicles from human milk‐fed infant digestive fluid

C Yung, Y Zhang, M Kuhn, RJ Armstrong… - Journal of …, 2024 - Wiley Online Library
Human milk contains extracellular vesicles (HMEVs). Pre‐clinical models suggest that
HMEVs may enhance intestinal function and limit inflammation; however, it is unknown if …

[HTML][HTML] Activation of coagulation FXI promotes endothelial inflammation and amplifies platelet activation in a nonhuman primate model of hyperlipidemia

TCL Kohs, HH Vu, KR Jordan, I Parra-Izquierdo… - Research and Practice …, 2024 - Elsevier
Background Hyperlipidemia is associated with chronic inflammation and
thromboinflammation. This is an underlying cause of several cardiovascular diseases …

Interplay of m6A RNA methylation and gut microbiota in modulating gut injury

H Wang, J Han, XA Zhang - Gut Microbes, 2025 - Taylor & Francis
The gut microbiota undergoes continuous variations among individuals and across their
lifespan, shaped by diverse factors encompassing diet, age, lifestyle choices, medication …

Role of the RNA binding protein IGF2BP1 in cancer multidrug resistance

AM Gola, M Bucci-Muñoz, JP Rigalli… - Biochemical …, 2024 - Elsevier
The insulin-like growth factor-2 mRNA-binding protein 1 (IGF2BP1), a member of a
conserved family of single-stranded RNA-binding proteins (IGF2BP1-3), is expressed in a …

Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) in hematological diseases

S Ma, Y Qin, W Ren - Molecular Medicine, 2024 - Springer
The oncofetal mRNA-binding protein IGF2BP1 belongs to a conserved family of RNA-
binding proteins. It primarily promotes RNA stability, regulates translation and RNA …

Characterization of butyrate-metabolism in colorectal cancer to guide clinical treatment

Q Luo, P Zhou, S Chang, Z Huang, X Zeng - Scientific Reports, 2023 - nature.com
Colorectal cancer (CRC) is the third most prevalent one in the world among the most
common malignant tumors. Numerous studies have shown that butyrate has demonstrated …

[HTML][HTML] Circulating Extracellular Vesicles: An Effective Biomarker for Cancer Progression

M Chatterjee, S Gupta, S Nag, I Rehman… - Frontiers in Bioscience …, 2024 - imrpress.com
Extracellular vesicles (EVs), the ubiquitous part of human biology, represent a small
heterogenous, membrane-enclosed body that contains a diverse payload including genetic …

Cholesterol deficiency directs autophagy-dependent secretion of extracellular vesicles

JDW Yaeger, S Sengupta, AL Walz, M Morita… - bioRxiv, 2025 - biorxiv.org
Extracellular vesicle (EV) secretion is an important, though not fully understood, intercellular
communication process. Lipid metabolism has been shown to regulate EV activity, though …