Platelets are anucleate cells produced by megakaryocytes. In recent years, a robust body of
literature supports the evolving role of platelets as key sentinel and effector cells in infectious …

Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …

Rationale: In addition to the overwhelming lung inflammation that prevails in coronavirus
disease 2019 (COVID-19), hypercoagulation and thrombosis contribute to the lethality of …

Thrombocytopenia, which signifies a low platelet count usually below 150× 109/L, is a
common finding following or during many viral infections. In clinical medicine, mild …

In addition to their hemostatic role, platelets play a significant role in immunity. Once
activated, platelets release extracellular vesicles (EVs) formed by the budding of their …

Platelets are classically recognized for their important role in hemostasis and thrombosis but
they are also involved in many other physiological and pathophysiological processes …

Viral infections are often associated with platelet activation and haemostatic complications.
In line, low platelet counts represent a hallmark for poor prognosis in many infectious …

The immune system is comprised of two principal interconnected components called innate
and adaptive immunity. While the innate immune system mounts a nonspecific response that …

Evolving evidence demonstrates that platelets have major roles in viral syndromes through
previously unrecognized viral sensing and effector functions. Activated platelets and …

Platelets, key facilitators of primary hemostasis and thrombosis, have emerged as crucial
cellular mediators of innate immunity and inflammation. Exemplified by their ability to alter …