Prostate-only versus whole-pelvic radiation therapy in high-risk and very high-risk prostate cancer (POP-RT): outcomes from phase III randomized controlled trial
PURPOSE We report the clinical outcomes of a randomized trial comparing prophylactic
whole-pelvic nodal radiotherapy to prostate-only radiotherapy (PORT) in high-risk prostate …
whole-pelvic nodal radiotherapy to prostate-only radiotherapy (PORT) in high-risk prostate …
Elective nodal radiotherapy in prostate cancer
G De Meerleer, C Berghen, A Briganti… - The Lancet …, 2021 - thelancet.com
In patients with prostate cancer who have a high risk of pelvic nodal disease, the use of
elective whole pelvis radiotherapy is still controversial. Two large, randomised, controlled …
elective whole pelvis radiotherapy is still controversial. Two large, randomised, controlled …
Management of patients with advanced prostate cancer. Report from the 2024 Advanced Prostate Cancer Consensus Conference (APCCC)
Background and objective: Innovations have improved outcomes in advanced prostate
cancer (PC). Nonetheless, we continue to lack high-level evidence on a variety of topics that …
cancer (PC). Nonetheless, we continue to lack high-level evidence on a variety of topics that …
Photon vs proton hypofractionation in prostate Cancer: A systematic review and meta-analysis
Background High-level evidence on hypofractionated proton therapy (PT) for localized and
locally advanced prostate cancer (PCa) patients is currently missing. The aim of this study is …
locally advanced prostate cancer (PCa) patients is currently missing. The aim of this study is …
[HTML][HTML] Sentinel node procedure to select clinically localized prostate cancer patients with occult nodal metastases for whole pelvis radiotherapy
HA de Barros, JJ Duin, D Mulder… - European Urology Open …, 2023 - Elsevier
Background Accurate identification of men who harbor nodal metastases is necessary to
select patients who most likely benefit from whole pelvis radiotherapy (WPRT). Limited …
select patients who most likely benefit from whole pelvis radiotherapy (WPRT). Limited …
Acute and late adverse effects of prostate-only or pelvic stereotactic radiation therapy in prostate cancer: a comparative study
Purpose To compare the urinary and gastrointestinal adverse effects with or without the
inclusion of pelvic nodal regions in patients treated with extreme hypofractionated …
inclusion of pelvic nodal regions in patients treated with extreme hypofractionated …
A randomized feasibility trial of stereotactic prostate radiation therapy with or without elective nodal irradiation in high-risk localized prostate cancer (sPORT trial)
OA Houlihan, K Redmond, C Fairmichael… - International Journal of …, 2023 - Elsevier
Purpose The aim of this study was to establish the feasibility of a randomized clinical trial
comparing SABR with prostate-only (P-SABR) or with prostate plus pelvic lymph nodes …
comparing SABR with prostate-only (P-SABR) or with prostate plus pelvic lymph nodes …
Late urinary toxicity and quality of life with pelvic radiation therapy for high-risk prostate cancer: dose-effect relations in the POP-RT randomized phase 3 trial
P Maitre, G Maheshwari, J Sarkar, P Singh… - International Journal of …, 2024 - Elsevier
Purpose The POP-RT phase 3 randomized trial showed improved biochemical failure-free
survival and metastasis-free survival with whole pelvic radiation therapy versus prostate …
survival and metastasis-free survival with whole pelvic radiation therapy versus prostate …
[HTML][HTML] A comparison between patient-and physician-reported late radiation toxicity in long-term prostate cancer survivors
AC Nuijens, AL Oei, A Bouhuijs, NAP Franken… - Cancers, 2022 - mdpi.com
Simple Summary Radiotherapy is widely used as treatment for localized prostate cancer.
Due to a high incidence and a good survival after treatment, a large number of prostate …
Due to a high incidence and a good survival after treatment, a large number of prostate …
Clinical outcomes of the CHIRP trial: A phase II prospective randomized trial of conventionally fractionated versus moderately hypofractionated prostate and pelvic …
Purpose Hypofractionated radiation therapy (HFRT) may offer treatment advantages for
patients with prostate cancer. However, HFRT may also increase the risk of gastrointestinal …
patients with prostate cancer. However, HFRT may also increase the risk of gastrointestinal …