To coordinate cellular physiology, eukaryotic cells rely on the rapid exchange of molecules
at specialized organelle–organelle contact sites,. Endoplasmic reticulum–mitochondrial …

Neurons are highly specialised cells that need to relay information over long distances and
integrate signals from thousands of synaptic inputs. The complexity of neuronal function is …

Organelle contact sites are regions where two heterologous membranes are juxtaposed by
molecular tethering complexes. These contact sites are important in inter-organelle …

The plant endoplasmic reticulum (ER) contacts heterotypic membranes at membrane
contact sites (MCSs) through largely undefined mechanisms. For instance, despite the well …

Effective intracellular communication between cellular organelles occurs at dedicated
membrane contact sites (MCSs). Tether proteins are responsible for the establishment of …

Signaling between the endoplasmic reticulum (ER) and mitochondria regulates many
neuronal functions that are perturbed in amyotrophic lateral sclerosis (ALS) and perturbation …

Acyl-CoA binding domain-containing proteins (ACBDs) perform diverse but often
uncharacterised functions linked to cellular lipid metabolism. Human ACBD4 and ACBD5 …

Sperm cryopreservation decreases motility, probably due to changes in protein
phosphorylation. Our objective was to use quantitative phosphoproteomics for systematic …

The glycolipid transfer protein (GLTP) has been linked to many cellular processes aside
from its best-known in vitro function as a lipid transport protein. It has been proposed to act …

In recent years, membrane contact sites (MCS), which mediate interactions between virtually
all subcellular organelles, have been extensively characterized and shown to be essential …