Factors affecting the preparation of nanocrystals: characterization, surface modifications and toxicity aspects

SM Marques, L Kumar - Expert Opinion on Drug Delivery, 2023 - Taylor & Francis
Introduction The fabrication of well-defined nanocrystals in size and form is the focus of
much investigation. In this work, we have critically reviewed several recent instances from …

Strategies to Enhance Nanocrystal Formulations for Overcoming Physiological Barriers Across Diverse Routes of Administration

Y Yanamadala, CMR Muthumula, S Khare… - International Journal …, 2025 - Taylor & Francis
Poor aqueous solubility and bioavailability limit the translation of new drug candidates into
clinical applications. Nanocrystal formulations offer a promising approach for improving the …

Enhancement of antifungal activity and transdermal delivery of 5-flucytosine via tailored spanlastic nanovesicles: Statistical optimization, in-vitro characterization, and …

AY Safhi, NR Naveen, KJ Rolla, PD Bhavani… - Frontiers in …, 2023 - frontiersin.org
Aim and background: This current study aimed to load 5-flucytosine (5-FCY) into spanlastic
nanovesicles (SPLNs) to make the drug more efficient as an antifungal and also to load the …

Design and evaluation of magnetic-targeted bilosomal gel for rheumatoid arthritis: flurbiprofen delivery using superparamagnetic iron oxide nanoparticles

RY Mushtaq, NR Naveen, KJ Rolla… - Frontiers in …, 2024 - frontiersin.org
Introduction The study aimed to systematically enhance the fabrication process of
flurbiprofen-loaded bilosomes (FSB) using Quality by Design (QbD) principles and Design of …

Optimization of Hempseed-added kombucha for increasing the antioxidant capacity, protein concentration, and total phenolic content

S Reyes-Flores, TSS Pereira, MM Ramírez-Rodrigues - Beverages, 2023 - mdpi.com
To enhance the effects of kombucha's beneficial compounds and their functional properties,
studies on kombucha fermentation using alternatives ingredients are needed. The aim of …

A study on the beech wood machining parameters optimization using response surface methodology

S Pakzad, S Pedrammehr, M Hejazian - Axioms, 2022 - mdpi.com
The surface quality of wooden products is of great importance to production industries. The
best surface quality requires a thorough understanding of the cutting parameters' effects on …

Optimization of simvastatin transdermal patch for hyperlipidemia treatment in rat model

Neetu, A Anand, D Panjwani - Future Journal of Pharmaceutical Sciences, 2024 - Springer
Abstract Objective Biopharmaceutics Classification System says that simvastatin (SMV) is a
Class II drug with low bioavailability (5%). This is because it dissolves slowly and is broken …

[HTML][HTML] Drug Nanocrystals in Oral Absorption: Factors That Influence Pharmacokinetics

LO Macedo, JF Masiero, NA Bou-Chacra - Pharmaceutics, 2024 - mdpi.com
Despite the safety and convenience of oral administration, poorly water-soluble drugs
compromise absorption and bioavailability. These drugs can exhibit low dissolution rates …

[HTML][HTML] Evaluation of Mucoadhesive Nano-Bilosomal In Situ Gels Containing Anti-Psychotic Clozapine for Treatment of Schizophrenia: In Vitro and In Vivo Studies

MH Abdallah, MM Shahien, HES El-Horany… - Pharmaceuticals, 2024 - mdpi.com
Background/Objectives: Patients with schizophrenia have significant challenges in adhering
to and complying with oral medicines, resulting in adverse consequences such as symptom …

[HTML][HTML] Closing Editorial: Advanced Polymeric Materials for Pharmaceutical Applications III

KN Kontogiannopoulos, P Barmpalexis - Polymers, 2024 - mdpi.com
This Special Issue on “Advanced Polymeric Materials for Pharmaceutical Applications III”
brings together innovative research that demonstrates the growing importance of polymeric …