Techniques to study antigen-specific B cell responses
Antibodies against foreign antigens are a critical component of the overall immune response
and can facilitate pathogen clearance during a primary infection and also protect against …
and can facilitate pathogen clearance during a primary infection and also protect against …
Memory B cells in multiple sclerosis: emerging players in disease pathogenesis
Multiple Sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system. Once thought to be primarily driven by T cells, B cells are emerging as central …
system. Once thought to be primarily driven by T cells, B cells are emerging as central …
Pattern of circulating SARS‐CoV‐2‐specific antibody‐secreting and memory B‐cell generation in patients with acute COVID‐19
Objectives To predict the spread of coronavirus disease (COVID‐19), information regarding
the immunological memory for disease‐specific antigens is necessary. The possibility of …
the immunological memory for disease‐specific antigens is necessary. The possibility of …
Memory B cells and memory T cells induced by SARS-CoV-2 booster vaccination or infection show different dynamics and responsiveness to the omicron variant
S Mise-Omata, M Ikeda, M Takeshita… - The Journal of …, 2022 - journals.aai.org
Although the immunological memory produced by BNT162b2 vaccination against severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been well studied and …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been well studied and …
Developability considerations for bispecific and multispecific antibodies
Bispecific antibodies (bsAb) and multispecific antibodies (msAb) encompass a diverse
variety of formats that can concurrently bind multiple epitopes, unlocking mechanisms to …
variety of formats that can concurrently bind multiple epitopes, unlocking mechanisms to …
[HTML][HTML] CpG 1018® adjuvant enhances Tdap immune responses against Bordetella pertussis in mice
Bordetella pertussis is the causative agent of whoo** cough (pertussis), a severe
respiratory disease that can be fatal, particularly in infants. Despite high vaccine coverage …
respiratory disease that can be fatal, particularly in infants. Despite high vaccine coverage …
B cell responses upon human papillomavirus (HPV) infection and vaccination
Infection with human papillomavirus (HPV) is the necessary cause of cervical cancer.
Availability of vaccines against HPV makes it a highly preventable disease. HPV vaccines …
Availability of vaccines against HPV makes it a highly preventable disease. HPV vaccines …
[HTML][HTML] A FluoroSpot B assay for the detection of IgA and IgG SARS-CoV-2 spike-specific memory B cells: Optimization and qualification for use in COVID-19 vaccine …
H Bisceglia, J Barrier, J Ruiz, A Pagnon - Journal of Immunological …, 2023 - Elsevier
Background The generation of antigen-specific memory B cells is crucial to the long-term
effectiveness of vaccines. When the protective antibodies circulating in the blood wane …
effectiveness of vaccines. When the protective antibodies circulating in the blood wane …
HBV induces inhibitory FcRL receptor on B cells and dysregulates B cell-T follicular helper cell axis
Spontaneous or treatment induced seroconversion in chronic HBV infection is rare and
generation of anti-HBs antibodies is the current goal of HBV therapeutics. Here we …
generation of anti-HBs antibodies is the current goal of HBV therapeutics. Here we …
Use of ELISpot assay to study HBs-specific B cell responses in vaccinated and HBV infected humans
C Tian, Y Chen, Y Liu, S Wang, Y Li… - Emerging Microbes & …, 2018 - Taylor & Francis
Hepatitis B surface antibody (HBsAb) plays a critical role in protecting against infection of
hepatitis B virus (HBV) and were extensively studied in literature. At the same time, the …
hepatitis B virus (HBV) and were extensively studied in literature. At the same time, the …