Mitogen-activated protein kinase (MAPK) cascades are universal, evolutionary conserved
signalling modules, which translate environmental information into appropriate responses …

Many fields of biology—including vertebrate Evo‐Devo research—are facing an explosion of
genomic and transcriptomic sequence information and a multitude of fish species are now …

In anamniote embryos, the major wave of zygotic genome activation starts during the mid-
blastula transition. However, some genes escape global genome repression, are activated …

Standard zebrafish transgenesis involves random transgene integration with resource-
intensive screening. While phiC31 integrase–based attP/attB recombination has streamlined …

Transgenic approaches are instrumental for labeling and manipulating cells and cellular
machineries in vivo. Transgenes have traditionally been static entities that remained …

Binocular stereopsis requires the convergence of visual information from corresponding
points in visual space seen by two different lines of sight. This may be achieved by …

Many eukaryotic genes play essential roles in multiple biological processes in several
different tissues. Conditional mutants are needed to analyze genes with such pleiotropic …

The use of transgenics in fish is a relatively recent development for advancing
understanding of genetic mechanisms and developmental processes, improving …

The goal of personalised medicine is to develop tailor-made therapies for patients in whom
currently available therapeutics fail. This approach requires correlating individual patient …

Mutations or genetic variation in noncoding regions of the genome harbouring cis-regulatory
elements (CREs), or enhancers, have been widely implicated in human disease and …