Hematopoietic stem cells (HSCs) are a rare, long-lived and multipotent population that give
rise to majority of blood cells and some tissue-resident immune cells. There is growing …

The response to type I IFNs involves the rapid induction of prototypical IFN signature genes
(ISGs). It is not known whether the tightly controlled ISG expression observed at the cell …

One of the first steps in single-cell omics data analysis is visualization, which allows
researchers to see how well-separated cell-types are from each other. When visualizing …

Inference of gene regulatory networks (GRNs) can reveal cell state transitions from single-
cell genomics data. However, obstacles to temporal inference from snapshot data are …

Stem cells display intrinsic interferon signaling, which protects them from viral infections. In
the aging brain, the increased presence of interferons drives a decline in function in neural …