Basal cell carcinoma (BCC) is the most common human cancer worldwide, and is a subtype
of nonmelanoma skin cancer, characterized by a constantly increasing incidence due to an …

The hedgehog (Hh) family comprises sonic hedgehog (Shh), Indian hedgehog (Ihh), and
desert hedgehog (Dhh), which are versatile signaling molecules involved in a wide …

Single particle cryogenic-electron microscopy (cryo-EM) is used extensively to determine
structures of activated G protein-coupled receptors (GPCRs) in complex with G proteins or …

As the most frequent and vulnerable malignancy among women, breast cancer universally
manifests a formidable healthcare challenge. From a biological and molecular perspective, it …

Anthranilic acid and its analogues present a privileged profile as pharmacophores for the
rational development of pharmaceuticals deliberated for managing the pathophysiology and …

Abstract Comparison of intratumor genetic heterogeneity in cancer at diagnosis and relapse
suggests that chemotherapy induces bottleneck selection of subclonal genotypes. However …

The hedgehog (Hh) pathway is a sophisticated conserved cell signaling pathway that plays
an essential role in controlling cell specification and proliferation, survival factors, and tissue …

Simple Summary Chronic myeloid leukaemia (CML) is a type of blood cancer that is
currently well-managed with drugs that target cancer-causing proteins. However, a …

Head and neck squamous cell carcinoma (HNSCC) is the sixth leading malignancy
worldwide, with a poor prognosis and limited treatment options. Molecularly targeted …

Abstract The Autism Spectrum Disorder (ASD) consists of a prevalent and heterogeneous
group of neurodevelopmental diseases representing a severe burden to affected individuals …