The first matrix metalloproteinase (MMP) was discovered in 1962 from the tail of a tadpole by
its ability to degrade collagen. As their name suggests, matrix metalloproteinases are …

The metalloproteinase (MP) family of zinc-dependent proteases, including matrix
metalloproteinases (MMPs), a disintegrin and metalloproteases (ADAMs), and a disintegrin …

Matrix metalloproteinases (MMPs) are identifiable members of proteolytic enzymes that can
degrade a wide range of proteins in the extracellular matrix (ECM). MMPs can be …

Since the identification of matrix metalloproteinases (MMPs), a family of zinc-dependent
endopeptidases, as being a driving factor for cancer progression and patient prognosis …

Chronic inflammation and fibrosis characterize Duchenne muscular dystrophy (DMD). We
show that pro-inflammatory macrophages are associated with fibrosis in mouse and human …

Over the last decade, significant progress has been made in the field of drug delivery. The
advent of engineered nanoparticles has allowed us to circumvent the initial limitations to …

The proteolytic processing of collagen (collagenolysis) is critical in development and
homeostasis, but also contributes to numerous pathologies. Mammalian interstitial …

Matrix metalloproteinases (MMPs) are the major protease family responsible for the
cleavage of the matrisome (global composition of the extracellular matrix (ECM) proteome) …

Natural killer (NK) cells are innate lymphocytes with cytotoxic functions and recognise target
cells with the NK group 2D (NKG2D) receptor. Tumor cells are marked for NK‐cell‐mediated …

Matrix metalloproteinases (MMPs) are a family of zinc endopeptidases that cleave nearly all
components of the extracellular matrix as well as many other soluble and cell‐associated …