Circadian control of pain and neuroinflammation

JP Segal, KA Tresidder, C Bhatt, I Gilron… - Journal of …, 2018‏ - Wiley Online Library
The importance of a neuroinflammatory response to the development and maintenance of
inflammatory and neuropathic pain have been highlighted in recent years. Inflammatory …

Circadian clock genes as promising therapeutic targets for autoimmune diseases

K **ang, Z Xu, YQ Hu, YS He, GC Wu, TY Li… - Autoimmunity …, 2021‏ - Elsevier
Circadian rhythm is a natural, endogenous process whose physiological functions are
controlled by a set of clock genes. Disturbance of the clock genes have detrimental effects …

A personalized signature and chronotherapy-based platform for improving the efficacy of sepsis treatment

A Kenig, Y Ilan - Frontiers in Physiology, 2019‏ - frontiersin.org
Sepsis remains a major therapeutic challenge and is associated with a high rate of morbidity
and mortality. It is a dynamic condition in which multiple parameters change over time …

Physical activity as a promising alternative for young people with juvenile idiopathic arthritis: Towards an evidence-based prescription

E Rochette, O Saidi, É Merlin, P Duché - Frontiers in immunology, 2023‏ - frontiersin.org
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in young people.
Although biologics now enable most children and adolescents with JIA to enjoy clinical …

The relationship between sleep and salivary and serum inflammatory biomarkers in adolescents

H Alqaderi, A Abdullah, M Finkelman… - Frontiers in …, 2023‏ - frontiersin.org
Objectives Poor sleep behavior can trigger an inflammatory response and contribute to the
development of inflammatory diseases. Cytokines can act as indicators of inflammation and …

Effect of agomelatine treatment on C-reactive protein levels in patients with major depressive disorder: an exploratory study in “real-world,” everyday clinical practice

D De Berardis, M Fornaro, L Orsolini, F Iasevoli… - CNS …, 2017‏ - cambridge.org
ObjectiveAgomelatine is a newer antidepressant but, to date, no studies have been carried
out investigating its effects on C-reactive protein (CRP) levels in major depressive disorder …

[HTML][HTML] Chronobiology and chronotherapy in inflammatory joint diseases

F Ursini, A De Giorgi, M D'Onghia, R De Giorgio… - Pharmaceutics, 2021‏ - mdpi.com
Circadian rhythm perturbations can impact the evolution of different conditions, including
autoimmune diseases. This narrative review summarizes the current understanding of …

Biological clock perspective in rheumatoid arthritis

Q Liu, Y Zhang - Inflammation, 2024‏ - Springer
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic
polyarticular pain, and its main pathological features include inflammatory cell infiltration …

Recent advances in the understanding of the aetiology and therapeutic strategies in burning mouth syndrome: Focus on the actions of cannabinoids

SR Pereira, J Tello Velasquez… - European Journal of …, 2022‏ - Wiley Online Library
Burning mouth syndrome (BMS) is a neuropathic pain disorder associated with a burning
sensation on oral mucosal surfaces with frequently reported xerostomia, dysgeusia and …

Circadian rhythm disorders elevate macrophages cytokines release and promote multiple tissues/organs dysfunction in mice

Z Sun, L Li, Z Yan, L Zhang, G Zang, Y Qian… - Physiology & …, 2022‏ - Elsevier
Background Circadian rhythm disorders are severe threats to human health. The negative
impact of circadian rhythm disorders on tissues/organs has not been systematically …