Natural products have played a critical role in medicine due to their ability to bind and
modulate cellular targets involved in disease. Medicinal plants hold a variety of bioactive …

Many prescriptions of traditional medicines (TMs), whose efficacy has been tested in clinical
practice, have great therapeutic value and represent an excellent resource for drug …

Despite massive investments in drug research and development, the significant decline in
the number of new drugs approved or translated to clinical use raises the question, whether …

Abstract Systems Bioinformatics is a relatively new approach, which lies in the intersection of
systems biology and classical bioinformatics. It focuses on integrating information across …

Diabetes mellitus (DM) is a kind of chronic and metabolic disease, which can cause a
number of diseases and severe complications. Network pharmacology approach is …

Traditional drug development for Alzheimer's disease (AD) is costly, time consuming and
burdened by a very low success rate. An alternative strategy is drug repositioning …

The concept of “network target” has ushered in a new era in the field of traditional Chinese
medicine (TCM). As a new research approach, network pharmacology is based on the …

In this paper, we propose DeCoST (Drug Repurposing from Control System Theory)
framework to apply control system paradigm for drug repurposing purpose. Drug …

Given the context of drug repurposing, there is a wealth of pharmacological and clinical
information available for drugs currently being prescribed that may provide a different …

Background: Drug discovery is one important issue in medicine and pharmacology area.
Traditional methods using target-based approach are usually time-consuming and …