Selenium is a trace mineral that is essential for health. After being obtained from food and
taken up by the liver, selenium performs various physiological functions in the body in the …

The reaction takes place at a specialized metal center that dramatically increases the acidity
of H2 and leads to a heterolytic splitting of the molecule which is strongly accelerated by the …

Abstract tRNAscan-SE has been widely used for transfer RNA (tRNA) gene prediction for
over twenty years, developed just as the first genomes were decoded. With the massive …

Abstract The Reference Sequence (RefSeq) project at the National Center for Biotechnology
Information (NCBI) provides annotation for over 95 000 prokaryotic genomes that meet …

The soil microbial community fulfils various functions, such as nutrient cycling and carbon
(C) sequestration, therefore contributing to maintenance of soil fertility and mitigation of …

The essential trace element, selenium (Se), has multiple biological activities, which depend
on the level of Se intake. Relatively low Se intakes determine the expression of …

Living organisms use selenium mainly in the form of selenocysteine in the active site of
oxidoreductases. Here, selenium's unique chemistry is believed to modulate the reaction …

Hydrogenase proteins catalyze the reversible conversion of molecular hydrogen to protons
and electrons. The most abundant hydrogenases contain a [NiFe] active site; these proteins …

At the time of its discovery four decades ago, the genetic code was viewed as the result of a
“frozen accident.” Our current knowledge of the translation process and of the detailed …

The defining entity of a selenoprotein is the inclusion of at least one selenocysteine (Sec)
residue in its sequence. Sec, the 21st naturally occurring genetically encoded amino acid …