Coherent anti-Stokes Raman scattering (CARS) microscopy can provide high resolution,
high speed, high sensitivity, and non-invasive imaging of specific biomolecules without …

Since the discovery of the inelastic scattering of light, ie, the so-called Raman effect, 1
Raman spectroscopy has become an attractive tool in a high number of research fields …

Intracellular lipid accumulation is commonly seen in fibrotic livers, but its exact role in liver
fibrosis remains elusive. Here, we established a multimodal nonlinear optical microscopy to …

Digital pathology (DP) has begun to play a key role in the evaluation of liver specimens.
Recent studies have shown that a workflow that combines DP and artificial intelligence (AI) …

Raman microspectroscopy is an emerging analytical tool that can monitor the biochemical
composition of biological or biomedical specimens, including proteins, cells, and tissues, as …

Electrochemical immunoassays are often used in the detection of biomarkers, and their
sensitivity depends on the nature of the substrate and the catalytic activity of the signal …

Background & Aims Peritoneal macrophages (PMs) regulate inflammation and control
bacterial infections in patients with decompensated cirrhosis. We aimed to characterize PMs …

Sepsis is an immune response to a microbial invasion that causes organ injury and
dysfunction due to a systemic inflammatory response. Sepsis is a serious, life-threatening …

As the state of resection margins is an important prognostic factor after extirpation of
colorectal liver metastases, surgeons aim to obtain negative margins, sometimes elaborated …

We demonstrate a multimodal nonlinear-optical imaging that combines second-and third-
harmonic generation (SHG and THG) with three-photon-excited fluorescence (3PEF) as a …