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Dynamics and functions of lipid droplets
Lipid droplets are storage organelles at the centre of lipid and energy homeostasis. They
have a unique architecture consisting of a hydrophobic core of neutral lipids, which is …
have a unique architecture consisting of a hydrophobic core of neutral lipids, which is …
The perilipin family of lipid droplet proteins: Gatekeepers of intracellular lipolysis
C Sztalryd, DL Brasaemle - Biochimica et biophysica acta (bba)-molecular …, 2017 - Elsevier
Lipid droplets in chordates are decorated by two or more members of the perilipin family of
lipid droplet surface proteins. The perilipins sequester lipids by protecting lipid droplets from …
lipid droplet surface proteins. The perilipins sequester lipids by protecting lipid droplets from …
Lipid droplet biogenesis
Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids for energy or
membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo …
membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo …
Lipid droplets: a cellular organelle vital in cancer cells
Y **, Y Tan, J Wu, Z Ren - Cell death discovery, 2023 - nature.com
Lipid droplets (LDs) are cellular organelles comprising a core of neutral lipids (glycerides,
sterols) encased within a single phospholipid membrane, responsible for storing surplus …
sterols) encased within a single phospholipid membrane, responsible for storing surplus …
The biophysics and cell biology of lipid droplets
Lipid droplets are intracellular organelles that are found in most cells, where they have
fundamental roles in metabolism. They function prominently in storing oil-based reserves of …
fundamental roles in metabolism. They function prominently in storing oil-based reserves of …
Seipin is required for converting nascent to mature lipid droplets
How proteins control the biogenesis of cellular lipid droplets (LDs) is poorly understood.
Using Drosophila and human cells, we show here that seipin, an ER protein implicated in …
Using Drosophila and human cells, we show here that seipin, an ER protein implicated in …
Targeting fat: mechanisms of protein localization to lipid droplets
How proteins specifically localize to the phospholipid monolayer surface of lipid droplets
(LDs) is being unraveled. We review here the major known pathways of protein targeting to …
(LDs) is being unraveled. We review here the major known pathways of protein targeting to …
The why, when and how of lipid droplet diversity
Lipid droplets are the universal cellular organelles for the transient or long-term storage of
lipids. The number, size and composition of lipid droplets vary greatly within cells in a …
lipids. The number, size and composition of lipid droplets vary greatly within cells in a …
Lipid droplet biogenesis
Lipid droplets (LDs) are found in most cells, where they play central roles in energy and
membrane lipid metabolism. The de novo biogenesis of LDs is a fascinating, yet poorly …
membrane lipid metabolism. The de novo biogenesis of LDs is a fascinating, yet poorly …