Quantitative phase imaging techniques for the study of cell pathophysiology: from principles to applications

KR Lee, K Kim, J Jung, JH Heo, S Cho, S Lee… - Sensors, 2013 - mdpi.com
A cellular-level study of the pathophysiology is crucial for understanding the mechanisms
behind human diseases. Recent advances in quantitative phase imaging (QPI) techniques …

Review of quantitative phase-digital holographic microscopy: promising novel imaging technique to resolve neuronal network activity and identify cellular biomarkers …

P Marquet, C Depeursinge, PJ Magistretti - Neurophotonics, 2014 - spiedigitallibrary.org
Quantitative phase microscopy (QPM) has recently emerged as a new powerful quantitative
imaging technique well suited to noninvasively explore a transparent specimen with a …

Host cell interactions of outer membrane vesicle-associated virulence factors of enterohemorrhagic Escherichia coli O157: Intracellular delivery, trafficking and …

M Bielaszewska, C Rüter, A Bauwens, L Greune… - PLoS …, 2017 - journals.plos.org
Outer membrane vesicles (OMVs) are important tools in bacterial virulence but their role in
the pathogenesis of infections caused by enterohemorrhagic Escherichia coli (EHEC) O157 …

Virulence from vesicles: Novel mechanisms of host cell injury by Escherichia coli O104:H4 outbreak strain

L Kunsmann, C Rüter, A Bauwens, L Greune… - Scientific reports, 2015 - nature.com
The highly virulent Escherichia coli O104: H4 that caused the large 2011 outbreak of
diarrhoea and haemolytic uraemic syndrome secretes blended virulence factors of …

Label-free cytotoxicity screening assay by digital holographic microscopy

J Kühn, E Shaffer, J Mena, B Breton… - Assay and drug …, 2013 - liebertpub.com
We introduce a label-free technology based on digital holographic microscopy (DHM) with
applicability for screening by imaging, and we demonstrate its capability for cytotoxicity …

Digital holographic microscopy: a quantitative label-free microscopy technique for phenotypic screening

B Rappaz, B Breton, E Shaffer… - … chemistry & high …, 2014 - ingentaconnect.com
Digital Holographic Microscopy (DHM) is a label-free imaging technique allowing
visualization of transparent cells with classical imaging cell culture plates. The quantitative …

Application of digital holographic microscopy to analyze changes in T-cell morphology in response to bacterial challenge

KL Vom Werth, B Kemper, S Kampmeier, A Mellmann - Cells, 2023 - mdpi.com
Quantitative phase imaging (QPI) is a non-invasive, label-free technique used to detect
aberrant cell morphologies caused by disease, thus providing a useful diagnostic approach …

Enterohemorrhagic Escherichia coli O157 outer membrane vesicles induce interleukin 8 production in human intestinal epithelial cells by signaling via Toll-like …

M Bielaszewska, M Marejková, A Bauwens… - International Journal of …, 2018 - Elsevier
Proinflammatory cytokines play important roles in the pathogenesis of diseases caused by
enterohemorrhagic Escherichia coli (EHEC) O157, but the spectrum of bacterial components …

Hemolysin of enterohemorrhagic Escherichia coli: structure, transport, biological activity and putative role in virulence

M Bielaszewska, T Aldick, A Bauwens… - International Journal of …, 2014 - Elsevier
Enterohemorrhagic Escherichia coli (EHEC) cause diarrhea, bloody diarrhea and hemolytic-
uremic syndrome (HUS), a thrombotic microangiopathy affecting the renal glomeruli, the …

Quantitative Stain-Free and Continuous Multimodal Monitoring of Wound Healing In Vitro with Digital Holographic Microscopy

D Bettenworth, P Lenz, P Krausewitz, M Brückner… - PloS one, 2014 - journals.plos.org
Impaired epithelial wound healing has significant pathophysiological implications in several
conditions including gastrointestinal ulcers, anastomotic leakage and venous or diabetic …