Saikosaponin-d (SSd) is a triterpene saponin from the roots of Bupleurum chinese. Recent
studies have revealed its antidepressant activity, but its mechanism involved is unclear. This …

Neurodegenerative disorders have a pathophysiology that heavily involves
neuroinflammation. In this study, we used lipopolysaccharide (LPS) to create a model of …

Aims Long-term neuroinflammation and brain dysfunction have frequently been reported in
sepsis survivors. In this study, the protective effect of memantine (an NMDA receptor …

Aim Sepsis-associated encephalopathy is a frequently observed consequence of sepsis,
often resulting in chronic brain inflammation and injury, ultimately leading to a range of …

Background Acute lung injury (ALI) remains a significant source of morbidity and mortality in
critically ill patients and currently there is no efficient therapy for this condition. The aim of …

Sepsis is associated with brain injury and acute brain inflammation, which can potentially
transition into chronic inflammation, triggering a cascade of inflammatory responses that …

Objective (s): Sepsis, a severe consequence of infection leading to organ failure, incites
damage in frequently affected brain tissue through inflammation and oxidative stress. This …

Aim: Sepsis is associated with brain injury and acute brain inflammation, which can
potentially transition into chronic inflammation, triggering a cascade of inflammatory …