Pyridine: the scaffolds with significant clinical diversity

S De, AK SK, SK Shah, S Kazi, N Sarkar, S Banerjee… - Rsc Advances, 2022 - pubs.rsc.org
The nitrogen-bearing heterocycle pyridine in its several analogous forms occupies an
important position as a precious source of clinically useful agents in the field of medicinal …

Electrochemical functionalization of imidazopyridine and indazole: An overview

D Ghosh, S Ghosh, A Hajra - Advanced Synthesis & Catalysis, 2021 - Wiley Online Library
Electrochemical synthesis offers a mild, simple, and efficient tool for the preparation of
interesting and useful molecules, thus eluding severe chemical oxidizing and reducing …

[KSIĄŻKA][B] Privileged structures in drug discovery: medicinal chemistry and synthesis

L Yet - 2018 - books.google.com
A comprehensive guide to privileged structures and their application in the discovery of new
drugs The use of privileged structures is a viable strategy in the discovery of new medicines …

Recent developments of imidazo [1, 2-a] pyridine analogues as antituberculosis agents

S Samanta, S Kumar, EK Aratikatla… - RSC Medicinal …, 2023 - pubs.rsc.org
Over the past 2000 years, tuberculosis (TB) has killed more people than any other infectious
disease. In 2021, TB claimed 1.6 million lives worldwide, making it the second leading …

Recent Progress in Metal-Free Direct Synthesis of Imidazo[1,2-a]pyridines

V Kurteva - ACS omega, 2021 - ACS Publications
This Mini-Review highlights the most effective protocols for metal-free direct synthesis of
imidazo [1, 2-a] pyridines, crucial target products and key intermediates, developed in the …

Solvent effect on molecular, electronic parameters, topological analysis and Fukui function evaluation with biological studies of imidazo [1, 2-a] pyridine-8-carboxylic …

S Selvakumari, KM Potla, D Shanthi, A Irfan… - Journal of Molecular …, 2023 - Elsevier
Abstract Imidazo [1, 2-a] pyridine-8-carboxylic acid, an aromatic molecule, was examined in
the current investigation applying the DFT approach exercising 6–311++ G (d, p) as a …

Recent Advances in the Synthesis of Imidazo[1,2‐a]pyridines: A Brief Review

J Panda, BP Raiguru, M Mishra, S Mohapatra… - …, 2022 - Wiley Online Library
This review focuses on providing comprehensive highlights of the recent synthetic pathways
of imidazo [1, 2‐a] pyridines, assisted through transition metal‐catalyzed reactions, multi …

IP‐Se‐06, a Selenylated Imidazo[1,2‐a]pyridine, Modulates Intracellular Redox State and Causes Akt/mTOR/HIF‐1α and MAPK Signaling Inhibition, Promoting …

DC Dos Santos, J Rafique, S Saba… - Oxidative Medicine …, 2022 - Wiley Online Library
Glioblastoma multiforme (GBM) is a notably lethal brain tumor associated with high
proliferation rate and therapeutic resistance, while currently effective treatment options are …

[HTML][HTML] Design, synthesis and biological evaluation of thiazole and imidazo [1, 2-a] pyridine derivatives containing a hydrazone substructure as potential …

X Yao, R Zhang, B Lv, WW Wang, Z Liu, Z Hu, D Li - Advanced Agrochem, 2023 - Elsevier
Agricultural chemicals with multifunctional applications in crop protection have attracted
increasing attention. Herein, two new series of thiazole and imidazo [1, 2-a] pyridine …

A review on the physiological and pathophysiological role of endothelial glycocalyx

H Liu, J Li, C Xuan, H Ma - Journal of biochemical and …, 2020 - Wiley Online Library
The glycocalyx is a gel‐like layer covering the luminal surface of vascular endothelial cells. It
comprises of membrane‐attached proteoglycans, glycosaminoglycan chains, glycoproteins …