Artificial intelligence with mass spectrometry-based multimodal molecular profiling methods for advancing therapeutic discovery of infectious diseases

J Liu, C Bao, J Zhang, Z Han, H Fang, H Lu - Pharmacology & Therapeutics, 2024‏ - Elsevier
Infectious diseases, driven by a diverse array of pathogens, can swiftly undermine public
health systems. Accurate diagnosis and treatment of infectious diseases—centered around …

A critical review on role of available synthetic drugs and phytochemicals in insulin resistance treatment by targeting PTP1B

P Rath, A Ranjan, A Chauhan, NK Verma… - Applied Biochemistry …, 2022‏ - Springer
Insulin resistance (IR) is a condition of impaired response of cells towards insulin. It is
marked by excessive blood glucose, dysregulated insulin signalling, altered pathways …

[HTML][HTML] Application of an innovative metabolomics approach to discriminate geographical origin and processing of black pepper by untargeted UHPLC-Q-Orbitrap …

A Rivera-Pérez, R Romero-González… - Food Research …, 2021‏ - Elsevier
An untargeted metabolomics approach based on ultra-high performance liquid
chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) …

Recent advancement in mass based plant metabolomics: techniques, tools, and analytical approaches

N Kumar, JS Bharat, A Kumar, V Jaitak - Phytochemistry Reviews, 2024‏ - Springer
Plant metabolomics, a rapidly advancing field within plant biology, is dedicated to
comprehensively exploring the intricate array of small molecules in plant systems. This …

Interactions between Phenols and Alkylamides of Sichuan Pepper (Zanthoxylum Genus) in α-Glucosidase Inhibition: A Structural Mechanism Analysis

D Zhang, X Liu, Z Yang, J Shi, L Zhao… - Journal of Agricultural …, 2021‏ - ACS Publications
The phenols and alkylamides in 26 varieties of Zanthoxylum pericarps (ZP) were
comparatively identified, and the contribution of these key components to the inhibition of in …

Near-infrared spectroscopy and HPLC combined with chemometrics for comprehensive evaluation of six organic acids in Ginkgo biloba leaf extract

S Zhang, X Gong, H Qu - Journal of Pharmacy and …, 2022‏ - academic.oup.com
Objectives To investigate the feasibility of using near-infrared spectroscopy for rapid
determination of main organic acids in Ginkgo biloba leaf extract (EGBL). Methods Main …

[HTML][HTML] Recent advances in NMR-based metabolomics of alcoholic beverages

MKAG Tabago, MN Calingacion, J Garcia - Food chemistry: Molecular …, 2021‏ - Elsevier
Alcoholic beverages have a complex chemistry that can be influenced by their alcoholic
content, origin, fermentation process, additives, and contaminants. The complex composition …

Potential of metabolomics in plant abiotic stress management

N Singh, A Mansoori, D Dey, R Kumar… - Omics Technologies for …, 2021‏ - Springer
Metabolomics reveals the metabolite profile of biological systems, its various chemical
compositions, its physiology, and complexity at a point in time. Metabolites are the main …

1H NMR-based metabolic profile and chemometric analysis for the discrimination of Passiflora species genotypic variations

LM Dutra, PHV Teles, AD da Conceição Santos… - Food Research …, 2023‏ - Elsevier
The species of the genus Passiflora (Passifloraceae family) have been used as food,
cosmetic and traditional herbal. As a result, the Passiflora species are widely cultivated and …

[PDF][PDF] A review of the Phyllanthus genus plants: Their phytochemistry, traditional uses, and potential inhibition of xanthine oxidase

H Husnunnisa, R Hartati, R Mauludin, M Insanu - Pharmacia, 2022‏ - pharmacia.pensoft.net
Hyperuricemia is a risk factor for gout and other cardiovascular diseases. One of the
therapies used is Allopurinol. Unfortunately, it has unwanted side effects. These conditions …